RecruitingDrug trialXCHT for Irinotecan-Induced Gut Toxicities (Randomized Controlled Trial)Randomized double-blind placebo-controlled trial (RCT) study, to determine the impact of XCHT on irinotecan-induced severe delayed-onset diarrhea (SDOD), and to determine the feasibility of using plasma raloxifene-4'-glucuronide as a probe for intestinal UGT activity.