RecruitingPhase 2Drug trialNALIRI-XELOX+AK104 for First-line Treatment of Advanced PDACThis study is a single-center, Phase II Study to assess the efficacy and safety of the regimen of Nanoliposomal Irinotecan and XELOX (NALIRI-XELOX) in combination with Cadonilimab in subjects with advanced pancreatic ductal adenocarcinoma who have not previously received systemic treatment.