RecruitingClinical trialMetabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)The purpose of this study is to refine and pilot an intervention using the Nicotine Metabolite Ratio (NMR) to inform the selection of pharmacologic treatment to increase smoking abstinence among Alaska Native and American Indian people. This is a single-arm pilot trial to assess and improve acceptability and feasibility.