RecruitingPhase 2Biological interventionPhase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous DiseaseThe goal of this study is to understand the safety, tolerability, and potential efficacy of an injected immune therapy called RP2 to treat oral precancer conditions and prevent progression to an oral cancer. The name of the study drug involved in this study is: -RP2 (a genetically modified live Herpes Simplex V-1 strain)