RecruitingPhase 2Drug trialEfficacy and Safety of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCLThe purpose of this study is to compare the efficacy and safety of genotype-guided targeted agents in combination with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone (Pola RCHP-X) versus Pola RCHP in Chinese patients with previously untreated diffuse large B-cell lymphoma (DLBCL).