RecruitingPhase 1Drug trialIntra-Arterial Magnesium Therapy After Mechanical Thrombectomy in Acute Ischemic StrokeThe goal of this Phase I unblinded, dose-escalation trial is to evaluate the safety and tolerability of intra-arterial magnesium sulfate injection after mechanical thrombectomy in patients experiencing acute ischemic stroke. This trial is one of the first trials to look at IA administration of magnesium sulfate into at risk brain tissue in a selective and localized fashion.