Apply to trial NCT07227610

A few quick questions so the study team can decide if you might be a fit.

RecruitingPhase 2Radiation therapy

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

This is a randomized, phase II trial comparing staged stereotactic radiosurgery (SSRS) versus fractionated stereotactic radiotherapy (FSRT) in patients with large brain metastases (≥2 cm and ≤5 cm). The study aims to evaluate efficacy, safety, and tumor response between these two standard-of-care radiation approaches.

How this works

Answer a few questions
About 5 to 10 minutes. Skip-friendly where possible.
We connect you with the study team
When a site picks up your application, we introduce you to their team directly — with you on the thread.
The team reaches out to schedule screening
Usually within a few business days, via the contact you give.

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Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

How this works

Answer a few questions

We connect you with the study team

The team reaches out to schedule screening