RecruitingDrug trialCR-001 in Adult Participants With Locally Advanced or Metastatic Solid TumorsThe purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.