RecruitingPhase 1Drug trialDose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy ParticipantsThe purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272 in combination with deutivacaftor (D-IVA) with or without tezacaftor (TEZ) in healthy subjects.