Apply to trial NCT07477691

A few quick questions so the study team can decide if you might be a fit.

RecruitingPhase 4Biological intervention

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

Study 165-401 is a Phase 4, open-label study designed to examine the concomitant use of methotrexate (MTX) to suppress immune responses to Palynziq and improve tolerability and efficacy in adults with PKU.

How this works

Answer a few questions
About 5 to 10 minutes. Skip-friendly where possible.
We connect you with the study team
When a site picks up your application, we introduce you to their team directly — with you on the thread.
The team reaches out to schedule screening
Usually within a few business days, via the contact you give.

EmailWe save your progress under this email and copy you when we connect you with the study team.

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

How this works

Answer a few questions

We connect you with the study team

The team reaches out to schedule screening