RecruitingPhase 4Drug trialThe Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)The VPT Safety Trial (VPS) compares two common antibiotic combinations to see how they affect the kidneys of patients in the hospital with serious infections. Both combinations are approved by the Food and Drug Administration (FDA). The goal is to help doctors know which combination is safer so they can make better choices for their patients.