Oncology Clinical Trials in Ann Arbor, MI

As of July 2026, 180 paid clinical trials are recruiting for Oncology in Ann Arbor, Michigan. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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181 clinical trials for Oncology

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Gilteritinib for the Treatment of ALK NSCLC

for Lung Non-Small Cell Carcinoma

Sites in Ann Arbor +2 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT06225427·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

Sites in Ann Arbor +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting·Listed Dec 2023

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Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

for Renal Cell Carcinoma

Drug: Nivolumab

Sites in Ann Arbor +5 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06053658·Phase 2·Recruiting·Listed Sep 2023

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

Sites in Ann Arbor +4 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting·Listed Feb 2021

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The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The RV-BOS Study)

for Bronchiolitis Obliterans Syndrome

Sites in Ann Arbor +3 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 8+

Code: NCT05250037·Recruiting·Listed Feb 2022

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Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

for Colorectal Adenomatous Polyp

Sites in Ann Arbor +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05630794·Phase 1·Recruiting·Listed Nov 2022

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Ann Arbor, Battle Creek +178 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

Sites in Ann Arbor +12 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting·Listed Oct 2021

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Ann Arbor +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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COMPASS Study for Metastatic Castration-resistant Prostate Cancer

for Prostate Cancer

Sites in Ann Arbor +2 more locations

Sponsor: Duke University

Sex: Male·Age: 18+

Code: NCT07050433·Recruiting·Listed Jul 2025

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Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

for Breast Atypical Hyperplasia

Sites in Ann Arbor +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 45 - 74·Accepts healthy volunteers

Code: NCT06195306·Phase 2·Recruiting·Listed Jan 2024

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Targeted Pediatric High-Grade Glioma Therapy

for High Grade Glioma

Sites in Ann Arbor +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05839379·Recruiting·Listed May 2023

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

Sites in Ann Arbor +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting·Listed May 2023

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Ann Arbor, Royal Oak +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Obeticholic Acid for Prevention in Barrett's Esophagus

for Barrett Esophagus

Sites in Ann Arbor +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04939051·Phase 2·Recruiting·Listed Jun 2021

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

Sites in Ann Arbor +15 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting·Listed Mar 2021

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An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

Sites in Ann Arbor, Chelsea +147 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting·Listed Jul 2020

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Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Venetoclax

Sites in Ann Arbor +3 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03523975·Phase 1, Phase 2·Recruiting·Listed May 2018

Apply to this trial

FITting Non-invasive Tests in Lynch Syndrome Surveillance

for Colorectal Cancer

Sites in Ann Arbor +2 more locations

Sponsor: University of Chicago

Sex: All·Age: 20 - 80

Code: NCT06898996·Recruiting·Listed Mar 2025

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CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer

for Breast Carcinoma

1 location in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT06915168·Recruiting·Listed Apr 2025

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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

Sites in Ann Arbor, Ypsilanti +140 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting·Listed Jun 2019

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Ann Arbor +13 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma

for Follicular Lymphoma

Drug: Rituximab

Sites in Ann Arbor +4 more locations

Sponsor: Juan P. Alderuccio, MD

Sex: All·Age: 18+

Code: NCT04998669·Phase 2·Recruiting·Listed Aug 2021

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Ann Arbor +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

for Hepatocellular Carcinoma

1 location in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT05901519·Phase 2·Recruiting·Listed Jun 2023

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Ann Arbor, Brighton +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in Ann Arbor, Brighton +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

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Repositioning Immunotherapy in VetArans With Lung Cancer

for Non-Small Cell Lung Cancer

Sites in Ann Arbor +6 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06275360·Phase 2·Recruiting·Listed Feb 2024

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

Sites in Ann Arbor, Ypsilanti +97 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Breast Cancer Resiliency Through Exercise Program (B-REP)

for Breast Cancer Female

1 location in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: Female·Age: 18+

Code: NCT06100263·Recruiting·Listed Oct 2023

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Precision-Based Genomics in Prostate Cancer

for Prostate Cancer

Sites in Ann Arbor +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04706663·Recruiting·Listed Jan 2021

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EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

for Non Small Cell Lung Cancer

Drug: Tulmimetostat

Sites in Ann Arbor +4 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05467748·Phase 1, Phase 2·Recruiting·Listed Jul 2022

Apply to this trial

National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

Sites in Ann Arbor, Detroit +16 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting·Listed Oct 2023

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Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for Barretts Esophagus With Dysplasia

Sites in Ann Arbor +22 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05753748·Recruiting·Listed Mar 2023

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Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

for Prostate Cancer

Sites in Ann Arbor +3 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT06084338·Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

for Prostate Cancer

1 location in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: Male·Age: 18+

Code: NCT05038332·Phase 2·Recruiting·Listed Sep 2021

Apply to this trial

EDRN Prostate MRI Biomarker Study

for PSA

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Male·Age: 18+

Code: NCT03784924·Recruiting·Listed Dec 2018

Apply to this trial

Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

Sites in Ann Arbor +28 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting·Listed Apr 2022

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Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

for Prostate Cancer

1 location in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: Male·Age: 40 - 80

Code: NCT05965180·Recruiting·Listed Jul 2023

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Excision of Lymph Node Trial (EXCILYNT) (Mel69)

for Melanoma

Sites in Ann Arbor +6 more locations

Sponsor: Craig L Slingluff, Jr

Sex: All·Age: 18+

Code: NCT05839912·Recruiting·Listed May 2023

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Conditions in Oncology (Ann Arbor, MI)

Solid tumor· 31 Non-small cell lung cancer (NSCLC)· 20 Breast cancer· 17 Colorectal cancer· 14 Prostate cancer· 14 Hematologic malignancy· 11 Melanoma· 10 Cancer (any)· 10 Acute myeloid leukemia (AML)· 9 Non-Hodgkin lymphoma· 8 Esophageal cancer· 7 Ovarian cancer· 7 Multiple myeloma· 7 Pancreatic cancer· 6 Biliary tract cancer· 6 Myelofibrosis· 6 Neuroblastoma· 6 Metastatic breast cancer· 5 Gastric cancer· 5 Bladder cancer· 5 Kidney cancer· 5 Lung cancer· 4 Liver cancer· 4 Metastatic prostate cancer· 4 Endometrial cancer· 4 Glioblastoma· 4 Leukemia (other)· 4 Myelodysplastic syndromes (MDS)· 4 Mantle cell lymphoma· 4 Head and neck cancer· 4 Gastroesophageal junction cancer· 3 Glioma· 3 Hodgkin lymphoma· 3 Triple-negative breast cancer· 2 HER2-negative breast cancer· 2 Chronic lymphocytic leukemia (CLL)· 2 Acute lymphoblastic leukemia· 2 Myeloproliferative neoplasm· 2 Follicular lymphoma· 2 Ewing sarcoma· 2 Neuroendocrine tumors· 2 HER2-positive breast cancer· 1 Fallopian tube cancer· 1 Brain metastases· 1 Diffuse large B-cell lymphoma (DLBCL)· 1 Marginal zone lymphoma· 1 Small lymphocytic lymphoma· 1 Thyroid cancer· 1 Sarcoma· 1 Osteosarcoma· 1 Pediatric cancer· 1 Mesothelioma· 1