Huntington's Disease — Trials, FDA Actions & Pivotal Research

20 active Huntington's Disease trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: August 19, 2026.

Find recruiting Huntington disease trials near you

Recruiting trials by city

Cities where Huntington's Disease trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Birmingham, AL Orlando, FL Boston, MA Columbus, OH Englewood, CO Irvine, CA La Jolla, CA Palo Alto, CA

Active Huntington's Disease trials

Currently recruiting US trials matching Huntington's Disease, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

Pridopidine Phase 3 Study in Huntington's Disease

for Huntington Disease

25 locations incl. Birmingham

Sponsor: Prilenia

Sex: All·Age: 23 - 65

Code: NCT07609108·Phase 3·Recruiting·Listed May 2026

Apply to this trial

A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease

for Huntington's Disease

Sponsor: Sarepta Therapeutics, Inc.

Sex: All·Age: 21 - 70

Code: NCT07536061·Phase 1·Recruiting·Listed Apr 2026

Apply to this trial

Mass Balance Study of [14C] LPM3770164 in Healthy Participants

for Huntington Disease

Sponsor: Luye Pharma Group Ltd.

Sex: Male·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07516899·Phase 1·Not Yet Recruiting·Listed Apr 2026

Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease

for Huntington Disease

Sponsor: First Affiliated Hospital of Fujian Medical University

Sex: All·Age: 18 - 75

Code: NCT07513844·Recruiting·Listed Apr 2026

Apply to this trial

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

for Huntington Disease

1 location in Irvine

Sponsor: Leslie Thompson

Sex: All·Age: 18 - 65

Code: NCT07451613·Phase 1, Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease

for Huntington Disease

Sponsor: University Hospital, Angers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07409597·Not Yet Recruiting·Listed Feb 2026

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

29 locations incl. La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

for Huntington Disease

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06634628·EARLY_Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

for Huntington Disease

2 locations incl. Rochester

Sponsor: BioSensics

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07315984·Not Yet Recruiting·Listed Jan 2026

Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

for Huntington Disease

Sponsor: Skyhawk Therapeutics, Inc.

Sex: All·Age: 25+

Code: NCT07378644·Phase 2, Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

for Huntington Disease

Sponsor: Region Skane

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07253038·Recruiting·Listed Nov 2025

Apply to this trial

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

for Huntington Disease

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 85

Code: NCT06843252·Recruiting·Listed Feb 2025

Apply to this trial

Hinting Task for Huntington's Disease

for Huntington Disease

Sponsor: University Medical Center Groningen

Sex: All·Age: 18 - 74

Code: NCT06774443·Recruiting·Listed Jan 2025

Apply to this trial

Transcranial Static Magnetic Stimulation (tSMS) in Huntington's Disease (HD)

for Huntington Disease

Sponsor: Neuromed IRCCS

Sex: All·Age: All ages

Code: NCT06976983·Not Yet Recruiting·Listed May 2025

Gut Microbiomes in HD

for Huntington Disease

1 location in Orlando

Sponsor: University of Central Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06448546·Recruiting·Listed Jun 2024

Apply to this trial

Cognitive Assessment Tools for Huntington's Disease.

for Huntington Disease

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 30 - 65

Code: NCT06546488·Recruiting·Listed Aug 2024

Apply to this trial

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

for Huntington Disease

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07010705·Recruiting·Listed Jun 2025

Apply to this trial

The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease

for Huntington Disease

Sponsor: Oslo University Hospital

Sex: All·Age: 18 - 80

Code: NCT06853743·Phase 2·Recruiting·Listed Mar 2025

Apply to this trial

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for Huntington Disease

5 locations incl. Boston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 65

Code: NCT06826612·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot Study

for Huntington Disease

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06626308·Recruiting·Listed Oct 2024

Apply to this trial