Hereditary Angioedema — Trials, FDA Actions & Pivotal Research

9 active Hereditary Angioedema trials currently recruiting in the US, sourced from ClinicalTrials.gov.

Synced daily from openFDA and ClinicalTrials.gov. Last sync: August 19, 2026.

Recruiting trials by city

Cities where Hereditary Angioedema trials in our archive had recruiting sites. Each link lists every currently recruiting paid clinical trial at that location.

Los Angeles, CA Birmingham, AL Colorado Springs, CO

Active Hereditary Angioedema trials

Currently recruiting US trials matching Hereditary Angioedema, sourced live from ClinicalTrials.gov. We’ll add per-event articles here as those trials post results or hit primary completion.

Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL)

for Hereditary Angioedema

1 location in Colorado Springs

Sponsor: KalVista Pharmaceuticals, Ltd.

Sex: All·Age: 12+

Code: NCT07654829·Phase 4·Not Yet Recruiting·Listed Jun 2026

Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

for Hemorrhoidal Bleeding

1 location in Los Angeles

Sponsor: Jessica K. Stewart, MD

Sex: All·Age: 18 - 89

Code: NCT07559630·Recruiting·Listed Apr 2026

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Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

15 locations incl. Litchfield Park

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting·Listed Feb 2026

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STOP-HAE: A Phase 3 Study of ADX-324 in HAE

for Hereditary Angioedema

15 locations incl. Litchfield Park

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06960213·Phase 3·Recruiting·Listed May 2025

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Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)

for Internal Hemorrhoids

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 90

Code: NCT07179601·Recruiting·Listed Sep 2025

Apply to this trial

Institutional Registry of Rare Diseases

for Rare Diseases

Sponsor: Hospital Italiano de Buenos Aires

Sex: All·Age: All ages

Code: NCT06573723·Recruiting·Listed Aug 2024

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Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002

for Hereditary Angioedema

Sponsor: Intellia Therapeutics

Sex: All·Age: All ages

Code: NCT06262399·Enrolling By Invitation·Listed Feb 2024

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

for Hereditary Angioedema

12 locations incl. Birmingham

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT05396105·Phase 2, Phase 3·Enrolling By Invitation·Listed May 2022

Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies

for Hereditary Angioedema

Sponsor: BioCryst Pharmaceuticals

Sex: All·Age: 2+

Code: NCT04933721·Phase 3·Enrolling By Invitation·Listed Jun 2021