Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

for Recurrent Ovarian Cancer

Sites in Los Angeles +6 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06365853·Phase 2·Recruiting·Listed Apr 2024

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Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)

for Stargardt Disease

Sites in San Francisco +9 more locations

Sponsor: Ascidian Therapeutics, Inc

Sex: All·Age: 12+

Code: NCT06467344·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Santa Monica +12 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting·Listed Mar 2025

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Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)

for Pulmonary Embolism Acute

Sites in Thousand Oaks +9 more locations

Sponsor: Akura Medical

Sex: All·Age: 18+

Code: NCT06672510·Recruiting·Listed Nov 2024

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A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in La Jolla +9 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06630234·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

Sites in Redwood City, Stockton +22 more locations

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting·Listed Nov 2022

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CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

for Relapsed/Refractory Acute Myeloid Leukemia (AML)

Sites in Los Angeles +8 more locations

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05143996·Phase 1·Recruiting·Listed Dec 2021

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A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis

for Prurigo Nodularis

Drug: Dupilumab

Sites in Palo Alto, Rancho Santa Margarita +12 more locations

Sponsor: Sanofi

Sex: All·Age: 6 Months - 17

Code: NCT06293053·Phase 3·Recruiting·Listed Mar 2024

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IC-8 Apthera IOL New Enrollment Post Approval Study

for Cataract

Sites in Newport Beach +13 more locations

Sponsor: Bausch & Lomb Incorporated

Sex: All·Age: 22+

Code: NCT06060041·Recruiting·Listed Sep 2023

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MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

for Coronary Artery Disease

Sites in Los Angeles +23 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 80

Code: NCT06271590·Recruiting·Listed Feb 2024

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TVMR With the INNOVALVE System Trial - Early Feasibility Study

for Mitral Valve Regurgitation (Degenerative or Functional)

Sites in Los Angeles, Palo Alto +17 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04919980·Recruiting·Listed Jun 2021

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Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

for Breast Reconstruction Surgery

Sites in Los Angeles, Irvine +18 more locations

Sponsor: W.L.Gore & Associates

Sex: Female·Age: 22+

Code: NCT06556654·Recruiting·Listed Aug 2024

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Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

for Low Risk Myelodysplastic Syndromes

Sites in Los Angeles, Palo Alto +11 more locations

Sponsor: Rigel Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05308264·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

Sites in Los Angeles, La Jolla +10 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

for Gastric Adenocarcinoma

Sites in Duarte, Irvine +12 more locations

Sponsor: Toray Industries, Inc

Sex: All·Age: 18+

Code: NCT06038578·Phase 2·Recruiting·Listed Sep 2023

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A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

for Hepatocellular Carcinoma

Drug: Livmoniplimab

Sites in Duarte, Orange +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06109272·Phase 2, Phase 3·Recruiting·Listed Oct 2023

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A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

for HER2-negative Breast Cancer Patients With Brain Metastases

Sites in Los Angeles, San Diego +15 more locations

Sponsor: Biostar Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06764940·Phase 2·Recruiting·Listed Jan 2025

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Minima Stent System Post- Approval Study (PAS)

for Pulmonary Artery Stenosis

Sites in Los Angeles +14 more locations

Sponsor: Renata Medical

Sex: All·Age: All ages

Code: NCT06828770·Recruiting·Listed Feb 2025

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

Sites in Orange, Sherman Oaks +9 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting·Listed Sep 2024

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

Drug: Repotrectinib

Sites in Los Angeles +11 more locations

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

Sites in San Diego +22 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting·Listed Jan 2022

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Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

for Myopia

Sites in San Francisco, San Diego +12 more locations

Sponsor: SightGlass Vision, Inc.

Sex: All·Age: 6 - 8·Accepts healthy volunteers

Code: NCT06034327·Recruiting·Listed Sep 2023

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A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

Sites in Los Angeles, Stanford +17 more locations

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting·Listed Jan 2023

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Serranator POINT FORCE Registry

for Peripheral Artery Disease (PAD)

Sites in Los Angeles +17 more locations

Sponsor: Cagent Vascular LLC

Sex: All·Age: 18+

Code: NCT06687590·Recruiting·Listed Nov 2024

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

Sites in San Francisco, Huntington Beach +13 more locations

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting·Listed Aug 2021

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AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for B-cell Malignancy

Sites in Orange +12 more locations

Sponsor: Carna Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05602363·Phase 1·Recruiting·Listed Nov 2022

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A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

for Breast Cancer

Sites in Los Angeles, Oxnard +11 more locations

Sponsor: Processa Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06568692·Phase 2·Recruiting·Listed Aug 2024

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Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

for AML, Adult

Sites in Duarte +10 more locations

Sponsor: Stelexis BioSciences

Sex: All·Age: 18+

Code: NCT06533761·Phase 1·Recruiting·Listed Aug 2024

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Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

for Metastatic Breast Cancer

Drug: Palazestrant

Sites in San Francisco +13 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05508906·Phase 1·Recruiting·Listed Aug 2022

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Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

for Colorectal Cancer

Sites in Fountain Valley +19 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05234177·Recruiting·Listed Feb 2022

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NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

Sites in Irvine, Glendale +8 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06911112·Phase 3·Recruiting·Listed Apr 2025

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Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies

for Advanced Solid Malignancies

Sites in Los Angeles, San Francisco +9 more locations

Sponsor: Georgiamune Inc

Sex: All·Age: 18+

Code: NCT06028074·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

for Lumbar Disc Disease

Sites in Santa Monica, Walnut Creek +12 more locations

Sponsor: BioRestorative Therapies

Sex: All·Age: 18+

Code: NCT04042844·Phase 2·Recruiting·Listed Aug 2019

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Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

for Von Willebrand Diseases

Sites in Los Angeles, Sacramento +8 more locations

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 60·Accepts healthy volunteers

Code: NCT05776069·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Los Angeles, Sacramento +13 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

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A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

for Cancer

Sites in Los Angeles +14 more locations

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT05970497·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

Sites in Palo Alto, Sacramento +17 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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AngelMed Guardian® System PMA Post Approval Study

for Acute Coronary Syndrome

Sites in Los Angeles +11 more locations

Sponsor: Angel Medical Systems

Sex: All·Age: 21+

Code: NCT05412927·Recruiting·Listed Jun 2022

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Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

for T-cell Lymphoma

Sites in Los Angeles, Duarte +8 more locations

Sponsor: SciTech Development, Inc.

Sex: All·Age: 18+

Code: NCT04234048·Phase 1·Recruiting·Listed Jan 2020

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

Sites in Los Angeles, San Francisco +7 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting·Listed Nov 2021

Apply to this trial