Clinical Trials at Cincinnati Children's Hospital Medical Center

As of June 2026, 281 paid clinical trials are recruiting at Cincinnati Children's Hospital Medical Center in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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281 clinical trials at Cincinnati Children's Hospital Medical Center

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A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

for Migraine

Drug: Rimegepant

27 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT06616194·Phase 3·Recruiting

Apply to this trial

Adolescent Outcomes of Post-operative Opioid EXposure

for Opioid Use Disorder

5 locations incl. Aurora

Sponsor: Sharon Levy

Sex: All·Age: 12 - 17

Code: NCT06350409·Recruiting

Apply to this trial

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

3 locations incl. Orange

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting

Apply to this trial

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

for Crohns Disease

Drug: Guselkumab

5 locations incl. Atlanta

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 3+

Code: NCT06663332·Phase 3·Recruiting

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A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

35 locations incl. California City

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

Apply to this trial

Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

10 locations incl. Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 21

Code: NCT06690801·Recruiting

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Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy

for DMD-Associated Dilated Cardiomyopathy

3 locations incl. Kansas City

Sponsor: Sardocor Corp.

Sex: Male·Age: 18+

Code: NCT06224660·Phase 1·Recruiting

Apply to this trial

Infant Formula in Infants and Children With Cow's Milk Allergy

for Cow's Milk Allergy

9 locations incl. Phoenix

Sponsor: Abbott Nutrition

Sex: All·Age: 3 Months - 12

Code: NCT06456541·Recruiting

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High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

for Immunization

8 locations incl. Stanford

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 17

Code: NCT05947071·Phase 2·Recruiting

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Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

for Duchenne Muscular Dystrophy

25 locations incl. Phoenix

Sponsor: Catalyst Pharmaceuticals, Inc.

Sex: Male·Age: 2+

Code: NCT06564974·Recruiting

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

Apply to this trial

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus of Childhood (Disorder)

6 locations incl. Birmingham

Sponsor: Michigan State University

Sex: All·Age: 12 - 22

Code: NCT06232304·Recruiting

Apply to this trial

SMART@Home Feasibility Trial

for Asthma

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 12 - 18

Code: NCT06159127·Recruiting

Apply to this trial

ADHD PreSMA Response Inhibition Therapy

for Attention Deficit Hyperactivity Disorder

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 12 - 17

Code: NCT06325813·Recruiting

Apply to this trial

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting

Apply to this trial

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

for Acute Kidney Injury

10 locations incl. Los Angeles

Sponsor: Talphera, Inc

Sex: All·Age: 18 - 80

Code: NCT06150742·Recruiting

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Targeted Pediatric High-Grade Glioma Therapy

for High Grade Glioma

11 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05839379·Recruiting

Apply to this trial

BE WELL With Migraine: Brain Education and WELLness With Migraine

for Migraine

3 locations incl. Cambridge

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05987592·Recruiting

Apply to this trial

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

13 locations incl. Aurora

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting

Apply to this trial

STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade

for Autism Spectrum Disorder

2 locations incl. Carrboro

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 15 - 21

Code: NCT06552286·Recruiting

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure

for Pediatric Intestinal Failure

8 locations incl. Boston

Sponsor: SterileCare Inc.

Sex: All·Age: 4 Weeks - 18

Code: NCT05879835·Recruiting

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The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

for Lupus Nephritis

19 locations incl. San Francisco

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 8 - 20

Code: NCT05538208·Phase 2·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

Apply to this trial

Prospective Clinical Assessment Study in Children With Hypochondroplasia

for Hypochondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 30 Months - 16

Code: NCT06410976·Recruiting

Apply to this trial

Spastic Paraplegia - Centers of Excellence Research Network

for Hereditary Spastic Paraplegia

11 locations incl. Miami

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06553976·Recruiting

Apply to this trial

Boosting Resources for Tracheostomy Care at Home

for Tracheostomy

6 locations incl. La Jolla

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06283953·Enrolling By Invitation

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

10 locations incl. San Diego

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting

Apply to this trial

ES Catheter vs Cryoablation After Pectus Surgery

for Pectus Excavatum

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 12 - 21

Code: NCT06682208·Recruiting

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NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

for Adipocytic Neoplasm

Drug: Selinexor

6 locations incl. Chicago

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06239272·Phase 1, Phase 2·Recruiting

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Recombinant Zoster Vaccine in Young Adult Solid Organ Transplant Recipients

for Varicella Zoster

3 locations incl. Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 19 - 40

Code: NCT06162494·Phase 4·Enrolling By Invitation

Spectral Lighting and Intestinal Failure

for Intestinal Failure

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 1

Code: NCT06094504·Enrolling By Invitation

NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

10 locations incl. Aurora

Sponsor: NS Pharma, Inc.

Sex: Male·Age: 4 - 14

Code: NCT05996003·Phase 2·Recruiting

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Mirdametinib in Histiocytic Disorders

for Langerhans Cell Histiocytosis (LCH)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2+

Code: NCT06153173·Phase 2·Recruiting

Apply to this trial

Chicago Parent Program for Foster and Kinship Caregivers

for Behavior Problem

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT06170047·Recruiting

Apply to this trial

Single Arm Romiplostim to Prevent CIT

for Ewings Sarcoma

2 locations incl. Phoenix

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1+

Code: NCT07048249·EARLY_Phase 1·Recruiting

Apply to this trial

Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)

for Non-Alcoholic Fatty Liver Disease

1 location in Cincinnati

Sponsor: Marialena Mouzaki

Sex: All·Age: 5 - 12

Code: NCT06133101·Phase 2·Recruiting

Apply to this trial

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

for Dystonia

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 - 21·Accepts healthy volunteers

Code: NCT07325175·Recruiting

Apply to this trial