Clinical Trials at Cincinnati Children's Hospital Medical Center

As of July 2026, 253 paid clinical trials are recruiting at Cincinnati Children's Hospital Medical Center, located at 3333 BURNET AVENUE, 11027, CINCINNATI, OH 45229, phone (513) 803-4738 in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 21, 2026.

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257 clinical trials at Cincinnati Children's Hospital Medical Center

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

Sites in Cincinnati +8 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting·Listed Sep 2019

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

Sites in Cincinnati +4 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting·Listed Nov 2023

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Cincinnati, Dayton +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

for Childhood Astrocytoma

Sites in Cincinnati +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 22

Code: NCT06894979·Phase 1·Recruiting·Listed Mar 2025

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Evaluating Additive Effects of Including Canines in Regulating Together

for Autism Spectrum Disorder

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 8 - 15

Code: NCT05803343·Recruiting·Listed Apr 2023

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NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

for Adipocytic Neoplasm

Drug: Selinexor

Sites in Cincinnati +6 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT06239272·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Cincinnati, Columbus +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Comparing Stainless Steel Crowns With Prefabricated Resin Crowns in Primary Molar Teeth

for Dental Caries

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2 - 5·Accepts healthy volunteers

Code: NCT06713330·Recruiting·Listed Dec 2024

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Cincinnati, Dayton +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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TReatment for ImmUne Mediated PathopHysiology

for Acute Liver Failure

Sites in Cincinnati +16 more locations

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 1 - 18

Code: NCT04862221·Phase 2·Recruiting·Listed Apr 2021

Apply to this trial

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

Sites in Cincinnati +2 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting·Listed Sep 2024

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Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

for Sickle Cell Disease

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT04093986·Recruiting·Listed Sep 2019

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The Congenital Dyserythropoietic Anemia Registry (CDAR)

for Congenital Dyserythropoietic Anemia (CDA)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02964494·Recruiting·Listed Nov 2016

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Mind Body Balance for Pediatric Migraine

for Headache

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17

Code: NCT04715685·Recruiting·Listed Jan 2021

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Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation

for Allogeneic Hematopoietic Cell Transplantation

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05501756·Phase 2·Recruiting·Listed Aug 2022

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Safety of RSV Preventive Monoclonal Antibody

for Fever

Sites in Cincinnati +4 more locations

Sponsor: Duke University

Sex: All·Age: 6 Weeks - 30 Weeks·Accepts healthy volunteers

Code: NCT07158814·Phase 4·Recruiting·Listed Sep 2025

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BE WELL With Migraine: Brain Education and WELLness With Migraine

for Migraine

Sites in Cincinnati +2 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05987592·Recruiting·Listed Aug 2023

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Cincinnati +9 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting·Listed Dec 2023

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Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

for Acute Pancreatitis

Sites in Cincinnati +2 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04195347·Phase 1, Phase 2·Recruiting·Listed Dec 2019

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A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

Sites in Cincinnati +3 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting·Listed Mar 2024

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PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

Sites in Cincinnati, Columbus +11 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting·Listed Oct 2021

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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

Sites in Cincinnati, Columbus +29 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting·Listed Jan 2023

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Cincinnati +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

for LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\)

Sites in Cincinnati, Columbus +12 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 5

Code: NCT06503367·Recruiting·Listed Jul 2024

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in Cincinnati +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

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Targeted Pediatric High-Grade Glioma Therapy

for High Grade Glioma

Sites in Cincinnati, Columbus +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05839379·Recruiting·Listed May 2023

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

Sites in Cincinnati, Columbus +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting·Listed May 2023

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High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

for Immunization

Sites in Cincinnati +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 17

Code: NCT05947071·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

for Adamantinomatous Craniopharyngioma

Sites in Cincinnati, Columbus +5 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 39

Code: NCT05233397·Phase 2·Recruiting·Listed Feb 2022

Apply to this trial

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

Sites in Cincinnati +33 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting·Listed May 2021

Apply to this trial

Ferric Citrate and Chronic Kidney Disease in Children

for Chronic Kidney Diseases

Sites in Cincinnati, Columbus +16 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 6 - 18

Code: NCT04741646·Phase 2·Recruiting·Listed Feb 2021

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Shwachman Diamond Syndrome Registry and Study

for Shwachman-Diamond Syndrome

Sites in Cincinnati +3 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06056908·Recruiting·Listed Sep 2023

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Cincinnati, Dayton +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) in Tuberculosis Patients

for Tuberculosis, Pulmonary

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+

Code: NCT07077213·Recruiting·Listed Jul 2025

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Sinus Disease in Young Children With Cystic Fibrosis

for Cystic Fibrosis in Children

Sites in Cincinnati +5 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 2 - 8

Code: NCT06191640·Recruiting·Listed Jan 2024

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MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

for Adamantinous Craniopharyngioma

Sites in Cincinnati, Columbus +3 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 39

Code: NCT05286788·Phase 2·Recruiting·Listed Mar 2022

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Evaluation of Analgesia for Spine Fusion Elective Surgery in Children

for Idiopathic Scoliosis

Sites in Cincinnati +1 more location

Sponsor: Senthil Sadhasivam

Sex: All·Age: 10 - 18

Code: NCT06626503·Phase 3·Recruiting·Listed Oct 2024

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Cincinnati, Columbus +30 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

Apply to this trial

SMART@Home Feasibility Trial

for Asthma

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 12 - 18

Code: NCT06159127·Recruiting·Listed Dec 2023

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The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

for Lupus Nephritis

Sites in Cincinnati, Columbus +17 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 8 - 20

Code: NCT05538208·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial