Clinical Trials at Cincinnati Children's Hospital Medical Center

As of July 2026, 253 paid clinical trials are recruiting at Cincinnati Children's Hospital Medical Center, located at 3333 BURNET AVENUE, 11027, CINCINNATI, OH 45229, phone (513) 803-4738 in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 21, 2026.

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257 clinical trials at Cincinnati Children's Hospital Medical Center

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

Sites in Cincinnati, Cleveland +20 more locations

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting·Listed Dec 2025

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

Sites in Cincinnati +20 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Cincinnati, Columbus +12 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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Adolescent Outcomes of Post-operative Opioid EXposure

for Opioid Use Disorder

Sites in Cincinnati +4 more locations

Sponsor: Sharon Levy

Sex: All·Age: 12 - 17

Code: NCT06350409·Recruiting·Listed Apr 2024

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A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

Sites in Cincinnati, Columbus +7 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting·Listed Dec 2020

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Single Arm Romiplostim to Prevent CIT

for Ewings Sarcoma

Sites in Cincinnati +1 more location

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1+

Code: NCT07048249·EARLY_Phase 1·Recruiting·Listed Jul 2025

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International Rare Brain Tumor Registry

for Astroblastoma

Sites in Cincinnati, Akron +4 more locations

Sponsor: Children's National Research Institute

Sex: All·Age: Up to 45

Code: NCT05697874·Recruiting·Listed Jan 2023

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Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders

for Fragile X Syndrome

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 5 - 10·Accepts healthy volunteers

Code: NCT06227780·Recruiting·Listed Jan 2024

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Responding With Evidence and Access for Childhood Headaches

for Headache

Sites in Cincinnati, Columbus +13 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17

Code: NCT05889624·Recruiting·Listed Jun 2023

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Cincinnati, Columbus +20 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

for Patellar Dislocation, Recurrent

Sites in Cincinnati, Dublin +14 more locations

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 10 - 35

Code: NCT06883396·Recruiting·Listed Mar 2025

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

Sites in Cincinnati +18 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

Chicago Parent Program for Foster and Kinship Caregivers

for Behavior Problem

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT06170047·Recruiting·Listed Dec 2023

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STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade

for Autism Spectrum Disorder

Sites in Cincinnati +1 more location

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 15 - 21

Code: NCT06552286·Recruiting·Listed Aug 2024

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Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

for Relapsed Hepatoblastoma

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05556642·Recruiting·Listed Sep 2022

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A National Registry For Pulmonary Alveolar Proteinosis

for Pulmonary Alveolar Proteinosis

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT02461615·Recruiting·Listed Jun 2015

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Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific T-cells for Viral Infections After Stem Cell Transplant

for Allogeneic Stell Cell Transplant

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT04230356·Phase 2·Recruiting·Listed Jan 2020

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Evaluation of the SMART IBD App in Pediatric IBD

for Inflammatory Bowel Disease (IBD)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT07195123·Recruiting·Listed Sep 2025

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in Cincinnati, Columbus +18 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

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Improving ADHD Teen Driving - Virtual Reality

for Attention Deficit Hyperactivity Disorder (ADHD)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 16 - 19

Code: NCT06960980·Recruiting·Listed May 2025

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Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2+

Code: NCT05580601·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)

for Hemophagocytic Lymphohistiocytoses

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05277272·Recruiting·Listed Mar 2022

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RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age

for Uveitis

Sites in Cincinnati +2 more locations

Sponsor: Meyer Children's Hospital IRCCS

Sex: All·Age: 1 - 16

Code: NCT06273748·Recruiting·Listed Feb 2024

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Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL

for B-cell Acute Lymphoblastic Leukemia

Drug: Venetoclax

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT06863259·Phase 1·Recruiting·Listed Mar 2025

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Thebaine Urine Testing

for Urine Specimen Collection

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07192887·Recruiting·Listed Sep 2025

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Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

for Leukemia

Drug: Venetoclax

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT03826992·Phase 1·Recruiting·Listed Feb 2019

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Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults

for Respiratory Disorders

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6+·Accepts healthy volunteers

Code: NCT02272049·Phase 1, Phase 2·Recruiting·Listed Oct 2014

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A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

for Primary Extra-cranial Solid Tumor

Sites in Cincinnati +4 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 1 - 21

Code: NCT04928677·Phase 1·Recruiting·Listed Jun 2021

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Cincinnati, Columbus +66 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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BSGM to Evaluate Patients With GI Symptoms

for Gastrointestinal Motility Disorders in Children

Sites in Cincinnati, Columbus +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 25·Accepts healthy volunteers

Code: NCT05880199·Recruiting·Listed May 2023

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I-InTERACT Preterm Parenting

for Child Behavior Problem

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 8·Accepts healthy volunteers

Code: NCT06767293·Recruiting·Listed Jan 2025

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in Cincinnati, Cleveland +112 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)

for Sickle Cell Anemia (HbSS)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 Months+

Code: NCT07177300·Phase 4·Recruiting·Listed Sep 2025

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ADHD PreSMA Response Inhibition Therapy

for Attention Deficit Hyperactivity Disorder

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 12 - 17

Code: NCT06325813·Recruiting·Listed Mar 2024

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Cincinnati, Dayton +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

for Tuberous Sclerosis Complex

1 location in Cincinnati

Sponsor: David M. Ritter

Sex: Female·Age: All ages

Code: NCT06160310·Recruiting·Listed Dec 2023

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A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma

for Blunt Trauma to Abdomen

Sites in Cincinnati, Columbus +4 more locations

Sponsor: University of California, Davis

Sex: All·Age: Up to 17

Code: NCT05910567·Recruiting·Listed Jun 2023

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in Cincinnati, Akron +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

Sites in Cincinnati, Columbus +38 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting·Listed Mar 2016

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Comparison of a Demand Oxygen Delivery

for Obstructive Apnea

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT06609694·Recruiting·Listed Sep 2024

Apply to this trial