Oncology Clinical Trials in Duarte, CA

As of July 2026, 263 paid clinical trials are recruiting for Oncology in Duarte, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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267 clinical trials for Oncology

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Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

for Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06249282·Phase 1·Recruiting·Listed Feb 2024

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Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

Sites in Duarte, Los Angeles & Stanford

Sponsor: Anusha Kalbasi

Sex: All·Age: 18 - 75

Code: NCT04119024·Phase 1·Recruiting·Listed Oct 2019

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CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for Acute Lymphoblastic Leukemia

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06059391·Phase 2·Recruiting·Listed Sep 2023

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Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

for Recurrent Diffuse Large B-Cell Lymphoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07042438·Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

Sites in Duarte, Upland +14 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting·Listed Jan 2024

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Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Nemtabrutinib

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06572618·Phase 2·Recruiting·Listed Aug 2024

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in Duarte, Pasadena +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

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Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

for Acute Leukemia

Drug: Revumenib

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 2+

Code: NCT06575296·Phase 1·Recruiting·Listed Aug 2024

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Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06543381·Phase 1·Recruiting·Listed Aug 2024

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Telehealth Intervention for Ostomy Self-Management

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06528990·Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Phase II Trial of Lung Chemoemobolization

for Lung Non-Small Cell Carcinoma

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672108·Phase 2·Recruiting·Listed Jan 2023

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CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672147·Phase 1·Recruiting·Listed Jan 2023

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

Sites in Duarte, South Pasadena +97 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting·Listed Jun 2023

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Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

for B-Cell Non-Hodgkin Lymphoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05432635·Phase 1·Recruiting·Listed Jun 2022

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Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

for Blastoid Variant Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT05861050·Phase 1, Phase 2·Recruiting·Listed May 2023

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Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05800405·EARLY_Phase 1·Recruiting·Listed Apr 2023

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Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

for Metastatic Malignant Solid Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05371132·Phase 1·Recruiting·Listed May 2022

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Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

for Cancer

Sites in Duarte, La Jolla & San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 0 - 50

Code: NCT05443737·Phase 3·Recruiting·Listed Jul 2022

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in Duarte, San Diego +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

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Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer

for Breast Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Female·Age: 21+·Accepts healthy volunteers

Code: NCT04913064·Recruiting·Listed Jun 2021

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Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

for Hematopoietic and Lymphoid System Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05772130·Recruiting·Listed Mar 2023

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Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for Lung Non-Small Cell Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05830058·Phase 2·Recruiting·Listed Apr 2023

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Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Glofitamab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06054776·Phase 2·Recruiting·Listed Sep 2023

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Duarte, Upland +124 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

for Bladder Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05519878·Recruiting·Listed Aug 2022

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PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

for Clinical Stage IV Gastric Cancer AJCC v8

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04329494·Phase 1·Recruiting·Listed Apr 2020

Apply to this trial

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

for Breast Carcinoma

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06731894·Phase 2·Recruiting·Listed Dec 2024

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Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06910761·Phase 2·Recruiting·Listed Apr 2025

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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Duarte +2 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03113643·Phase 1·Recruiting·Listed Apr 2017

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Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Arcadia +5 more locations

Sponsor: City of Hope Medical Center

Sex: Female·Age: 40+

Code: NCT06954831·Phase 2·Recruiting·Listed May 2025

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Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Ruxolitinib

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 2 - 22

Code: NCT06128070·Phase 2·Recruiting·Listed Nov 2023

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Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

for Lung Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05384769·Recruiting·Listed May 2022

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Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06260033·Phase 2·Recruiting·Listed Feb 2024

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Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

for Advanced Prostate Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 60+

Code: NCT05869682·Phase 2·Recruiting·Listed May 2023

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Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

for Hematopoietic and Lymphoid System Neoplasm

Sites in Duarte, Upland & Lancaster

Sponsor: City of Hope Medical Center

Sex: All·Age: 65+

Code: NCT06022965·Recruiting·Listed Sep 2023

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Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

for B-Cell Non-Hodgkin Lymphoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+

Code: NCT06052826·Phase 2·Recruiting·Listed Sep 2023

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Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

for Marginal Zone Lymphoma

Sites in Duarte +3 more locations

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05296070·Phase 2·Recruiting·Listed Mar 2022

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External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease

for Extramedullary Disease in Multiple Myeloma

Drug: Talquetamab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06572605·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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AOH1996 for the Treatment of Refractory Solid Tumors

for Refractory Malignant Solid Neoplasm

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05227326·Phase 1·Recruiting·Listed Feb 2022

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Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases

for Metastatic Malignant Neoplasm in the Bone

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06549478·Phase 1·Recruiting·Listed Aug 2024

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Conditions in Oncology (Duarte, CA)

Solid tumor· 45 Acute myeloid leukemia (AML)· 30 Non-small cell lung cancer (NSCLC)· 27 Myelodysplastic syndromes (MDS)· 25 Hematologic malignancy· 23 Breast cancer· 22 Prostate cancer· 19 Colorectal cancer· 17 Pancreatic cancer· 15 Ovarian cancer· 15 Esophageal cancer· 14 Non-Hodgkin lymphoma· 14 Cancer (any)· 14 Metastatic breast cancer· 13 Multiple myeloma· 13 Gastric cancer· 12 Acute lymphoblastic leukemia· 11 Head and neck cancer· 11 Endometrial cancer· 10 Leukemia (other)· 10 Diffuse large B-cell lymphoma (DLBCL)· 10 Bladder cancer· 9 Myelofibrosis· 9 Lung cancer· 8 Gastroesophageal junction cancer· 7 Kidney cancer· 7 Chronic lymphocytic leukemia (CLL)· 7 Hodgkin lymphoma· 7 Mantle cell lymphoma· 7 Melanoma· 7 Liver cancer· 6 Biliary tract cancer· 6 Cervical cancer· 6 Triple-negative breast cancer· 5 Myeloproliferative neoplasm· 5 Small lymphocytic lymphoma· 5 Metastatic prostate cancer· 4 Follicular lymphoma· 4 Marginal zone lymphoma· 4 Sarcoma· 4 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Glioblastoma· 3 Neuroendocrine tumors· 3 Small cell lung cancer· 2 Chronic myelomonocytic leukemia· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Neuroblastoma· 1