Clinical Trials at City of Hope

As of July 2026, 123 paid clinical trials are recruiting at City of Hope, located at 1500 DUARTE RD, DUARTE, CA 91010-3012, phone (626) 256-4673 in Duarte, California. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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124 clinical trials at City of Hope

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A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

for Myelofibrosis

Drug: Ruxolitinib

Sites in Duarte, Irvine +4 more locations

Sponsor: Geron Corporation

Sex: All·Age: 18+

Code: NCT05371964·Phase 1·Recruiting·Listed May 2022

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Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

for Leukemia, Myeloid, Chronic

Sites in Duarte +7 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT04260022·Phase 1·Recruiting·Listed Feb 2020

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A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

for Recurrent Head and Neck Squamous Cell Carcinoma

Sites in Duarte +6 more locations

Sponsor: Rakuten Medical, Inc.

Sex: All·Age: 18+

Code: NCT06699212·Phase 3·Recruiting·Listed Nov 2024

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Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

for Non-Hodgkin Lymphoma, Adult

Sites in Duarte +6 more locations

Sponsor: Marker Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05798897·Phase 1·Recruiting·Listed Apr 2023

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A Long Term Follow-up Study of TScan TCR-T Products

for AML

Sites in Duarte +1 more location

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18 - 110

Code: NCT06976736·Recruiting·Listed May 2025

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A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for Solid Tumors

Sites in Duarte, Santa Monica +6 more locations

Sponsor: Adcentrx Therapeutics

Sex: All·Age: 18+

Code: NCT06710379·Phase 1·Recruiting·Listed Nov 2024

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Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

for Locally Advanced Unresectable Pancreatic Adenocarcinoma

Sites in Duarte & Irvine

Sponsor: Impact Biotech Ltd

Sex: All·Age: 18+

Code: NCT05919238·Phase 1·Recruiting·Listed Jun 2023

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A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

for Acute Leukemia

Sites in Duarte +8 more locations

Sponsor: Ossium Health, Inc.

Sex: All·Age: 18 - 75

Code: NCT05589896·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

Sites in Duarte, San Francisco +6 more locations

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for Cancer

Sites in Duarte, Palo Alto +3 more locations

Sponsor: RefleXion Medical

Sex: All·Age: All ages

Code: NCT05406167·Recruiting·Listed Jun 2022

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A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

Sites in Duarte +6 more locations

Sponsor: Iterion Therapeutics

Sex: All·Age: 18+

Code: NCT05797805·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for CLL/SLL

Sites in Duarte +6 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18 - 85

Code: NCT04215809·Phase 1·Recruiting·Listed Jan 2020

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64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

for Metastatic Sarcoma

Sites in Duarte, Orange +3 more locations

Sponsor: Lantheus Medical Imaging

Sex: All·Age: 15+

Code: NCT06298916·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects with Any Progressive Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Duarte, Los Angeles +3 more locations

Sponsor: ABL Bio, Inc.

Sex: All·Age: 18+

Code: NCT04762641·Phase 1·Recruiting·Listed Feb 2021

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Study of SIRPant-M in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma

for Refractory Non-Hodgkin Lymphoma

Sites in Duarte +2 more locations

Sponsor: SIRPant Immunotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05967416·Phase 1·Recruiting·Listed Aug 2023

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Study of REM-422 in Patients With AML or Higher Risk MDS

for Myelodysplastic Syndromes

Sites in Duarte +4 more locations

Sponsor: Remix Therapeutics

Sex: All·Age: 18+

Code: NCT06297941·Phase 1·Recruiting·Listed Mar 2024

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Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

Sites in Duarte +4 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting·Listed Jun 2024

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Duarte, Glendale +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Duarte, Los Angeles +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Duarte, La Jolla +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Duarte, Burbank +41 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

Sites in Duarte +1 more location

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05136846·Phase 1·Recruiting·Listed Nov 2021

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The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

for Peripheral Blood Stem Cell Transplantation

Sites in Duarte +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT05436418·Phase 1, Phase 2·Recruiting·Listed Jun 2022

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Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for Bone Pain

Sites in Duarte, Los Angeles +7 more locations

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT03858205·Recruiting·Listed Feb 2019

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Duarte, Stanford +7 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

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Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

for Chronic Graft Versus Host Disease

Sites in Duarte +4 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05996627·Phase 2·Recruiting·Listed Aug 2023

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Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

Sites in Duarte, Newport Beach +57 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting·Listed Dec 2022

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A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

for Prostate Cancer (Adenocarcinoma)

Sites in Duarte +6 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 18+

Code: NCT06844383·Phase 2·Recruiting·Listed Feb 2025

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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for Prostate Carcinoma

Sites in Duarte, San Francisco +5 more locations

Sponsor: University of Washington

Sex: Male·Age: 40+·Accepts healthy volunteers

Code: NCT04472338·Recruiting·Listed Jul 2020

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A Global Study of the PETAL Consortium

for T-Cell and NK-Cell Neoplasm

Sites in Duarte +9 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06067347·Recruiting·Listed Oct 2023

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A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for AML (Acute Myelogenous Leukemia)

Sites in Duarte, Palo Alto +11 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 66

Code: NCT06859424·Phase 2·Recruiting·Listed Mar 2025

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Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

Sites in Duarte, Los Angeles & Stanford

Sponsor: Anusha Kalbasi

Sex: All·Age: 18 - 75

Code: NCT04119024·Phase 1·Recruiting·Listed Oct 2019

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Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

for Severe Aplastic Anemia

Sites in Duarte, Los Angeles +23 more locations

Sponsor: Medical College of Wisconsin

Sex: All·Age: 3 - 75

Code: NCT06517641·Phase 2·Recruiting·Listed Jul 2024

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Duarte +4 more locations

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting·Listed Feb 2025

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Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for T-Cell Neoplasm

Drug: Pacritinib

Sites in Duarte +5 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT04858256·Phase 2·Recruiting·Listed Apr 2021

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Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

for Castration-resistant Prostate Cancer

Drug: Apalutamide

Sites in Duarte, Los Angeles +1 more location

Sponsor: Edwin Posadas, MD

Sex: Male·Age: 18+

Code: NCT05534646·Phase 2·Recruiting·Listed Sep 2022

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Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients

for Cancer

Sites in Duarte, La Jolla & San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 0 - 50

Code: NCT05443737·Phase 3·Recruiting·Listed Jul 2022

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Duarte, Upland +124 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

for Mycosis Fungoides

Sites in Duarte, Palo Alto +5 more locations

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT02848274·Recruiting·Listed Jul 2016

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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Duarte +2 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03113643·Phase 1·Recruiting·Listed Apr 2017

Apply to this trial