Paid Clinical Trials in Illinois

Illinois has 2,972 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 24, 2026.

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2,975 clinical trials

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Proton or Photon RT for Retroperitoneal Sarcomas

for Retroperitoneal Sarcoma

10 locations incl. Chicago

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT01659203·Phase 1, Phase 2·Recruiting

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RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

for Pain

67 locations incl. Phoenix

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01719055·Recruiting

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Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

for Legg Calve Perthes Disease

28 locations incl. Birmingham

Sponsor: Texas Scottish Rite Hospital for Children

Sex: All·Age: 1 - 18

Code: NCT02040714·Enrolling By Invitation

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

62 locations incl. Birmingham

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting

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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

24 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting

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Islet Transplantation in Patients With "Brittle" Type I Diabetes

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT01630850·Recruiting

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Patient Retrospective Outcomes (PRO)

for Chronic Pain

87 locations incl. Lake Havasu City

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01550575·Recruiting

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

71 locations incl. Birmingham

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting

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Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

for Prostate Cancer

4 locations incl. Scottsdale

Sponsor: Proton Collaborative Group

Sex: Male·Age: 18+

Code: NCT01492972·Phase 3·Recruiting

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Product Surveillance Registry

for Cardiac Rhythm Disorders

134 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Functional Assessment in Liver Transplantation

for End Stage Liver Disease

12 locations incl. Little Rock

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03228290·Recruiting

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American Joint Replacement Registry

for ARTHROPLASTY, REPLACEMENT

1 location in Rosemont

Sponsor: American Joint Replacement Registry

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01909375·Recruiting

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Neuroblastoma Biology Study

for Neuroblastoma

16 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting

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Clinical and Genetic Analysis of ROP

for Retinopathy of Prematurity

5 locations incl. Palo Alto

Sponsor: Oregon Health and Science University

Sex: All·Age: Up to 1·Accepts healthy volunteers

Code: NCT04420156·Recruiting

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Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

for Down Syndrome

12 locations incl. Birmingham

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+

Code: NCT01429389·Recruiting

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The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

for Patients Undergoing Routine Health Care

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01280825·Recruiting

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Islet Transplantation in Type 1 Diabetic Kidney Allograft

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 68

Code: NCT01241864·Phase 2·Recruiting

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Caris Biorepository Research Protocol

for Cancer

38 locations incl. Mobile

Sponsor: Caris Science, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01499394·Recruiting

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

16 locations incl. Birmingham

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting

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One-Time DNA Study for Vasculitis

for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)

11 locations incl. Los Angeles

Sponsor: University of Pennsylvania

Sex: All·Age: 7+

Code: NCT01241305·Recruiting

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Natural History Study of SCID Disorders

for Severe Combined Immunodeficiency (SCID)

39 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT01186913·Enrolling By Invitation

Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

39 locations incl. Los Angeles

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting

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Proteogenomic Monitoring and Assessment of Kidney Transplant Recipients

for Acute Rejection (AR) of Transplanted Kidney

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT01531257·Recruiting

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Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

for Liver Transplant

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT01644903·Recruiting

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The Treatment of Type I Open Fractures in Pediatrics

for Fractures, Open

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 3 - 14

Code: NCT00870064·Recruiting

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

63 locations incl. Birmingham

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

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Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for Normal and Diseased Tissue and Body Fluids Samples

14 locations incl. Huntsville

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01354002·Recruiting

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Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

for Prostate Cancer

6 locations incl. Little Rock

Sponsor: Proton Collaborative Group

Sex: Male·Age: 18+

Code: NCT00969111·Recruiting

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Registry Study for Radiation Therapy Outcomes

for Neoplasms

29 locations incl. Scottsdale

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting

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Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

for Gastric Cancers

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: All ages

Code: NCT01416714·Recruiting

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Genetic Modifiers of Cystic Fibrosis Related Diabetes

for Cystic Fibrosis Related Diabetes

3 locations incl. Chicago

Sponsor: Johns Hopkins University

Sex: All·Age: 3 Months - 99·Accepts healthy volunteers

Code: NCT01113216·Enrolling By Invitation

The Pediatric Anesthesia Quality Improvement Project

for Surgery

37 locations incl. Phoenix

Sponsor: The Society for Pediatric Anesthesia

Sex: All·Age: Up to 21

Code: NCT00674388·Recruiting

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Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

24 locations incl. Laguna Woods

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting

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Language in Primary Progressive Aphasia

for Primary Progressive Aphasia

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: All ages

Code: NCT00537004·Recruiting

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Biliary Atresia Study in Infants and Children

for Biliary Atresia

15 locations incl. Los Angeles

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 6 Months - 20

Code: NCT00345553·Recruiting

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Explanted Lung Tissues With Pulmonary Fibrosis

for Pulmonary Fibrosis

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT00515567·Recruiting

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)

for Interstitial Lung Diseases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00470327·Recruiting

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Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

for Congenital Diaphragmatic Hernia

13 locations incl. Chicago

Sponsor: Columbia University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT00950118·Recruiting

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