Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,602 clinical trials

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Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

for Multiple Myeloma

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06483139·Recruiting

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Aim 2 - Conversations Can Save Lives: TALKing About Buprenorphine & Methadone for Opioid Use Treatment Initiation

for Opioid Use Disorder

1 location in Springfield

Sponsor: Baystate Medical Center

Sex: All·Age: 18+

Code: NCT06527820·Recruiting

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Mixed Vs Blocked Search: Four Unique Tasks

for Vision

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06933693·Recruiting

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Experiment 2: One Target in Many Situations

for Vision

1 location in Newton

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06934148·Recruiting

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Experiment 3: Mixed vs Blocked; Dashboard Paradigm

for Vision

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06934213·Recruiting

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Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

31 locations incl. Birmingham

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting

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Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

for Diabetes Mellitus, Type 1

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 5 - 12

Code: NCT05899166·Recruiting

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Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma

for Relapsed Cancer

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05922501·Phase 2·Recruiting

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BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

for Bronchiolitis Obliterans Syndrome

6 locations incl. Stanford

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05922761·Phase 2·Recruiting

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Health Outcomes of Parents With Cystic Fibrosis-Aim 2

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06296394·Recruiting

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CraniSeal Post Approval Study

for Leak, Cerebrospinal Fluid

8 locations incl. Los Angeles

Sponsor: Pramand LLC

Sex: All·Age: 18+

Code: NCT06406790·Phase 4·Recruiting

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Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

for Acute Myeloid Leukemia

Drug: Venetoclax

9 locations incl. New Haven

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06419634·Phase 1·Recruiting

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Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

31 locations incl. Birmingham

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting

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Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

for Relapsed or Refractory Multiple Myeloma

6 locations incl. Phoenix

Sponsor: Jiangsu Simcere Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT06375044·Phase 1·Recruiting

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Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

11 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

135 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting

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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

32 locations incl. Chandler

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting

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Continuous Glucose Monitor Use in Pregnancy

for Type 2 Diabetes Treated With Insulin

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT05317585·Recruiting

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CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

for End-Stage Kidney Disease

8 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05931276·Phase 3·Recruiting

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Advancing Transplantation Outcomes in Children

for Kidney Transplant

20 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 13 - 20

Code: NCT06055608·Phase 2·Recruiting

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

13 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting

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This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

for Non Small Cell Lung Cancer

3 locations incl. Boston

Sponsor: Zumutor Biologics Inc.

Sex: All·Age: 18+

Code: NCT06451497·Phase 1·Recruiting

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A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

for Small Cell Lung Cancer

30 locations incl. Springdale

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06203210·Phase 3·Recruiting

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A Study of SNDX-5613 in Combination With Intensive Chemotherapy in Participants With Acute Myeloid Leukemias

for Acute Myeloid Leukemias

26 locations incl. Burbank

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06226571·Phase 1·Recruiting

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A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

for Breast Neoplasms

82 locations incl. Tucson

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT06157892·Phase 2·Recruiting

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VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

84 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting

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Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for Asthma

105 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 12 - 17

Code: NCT06307665·Phase 3·Recruiting

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Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

46 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06158841·Phase 3·Recruiting

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An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.

for Cancer

1 location in Watertown

Sponsor: Hercules

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06212479·Recruiting

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Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy

for Food Allergy

Drug: Linvoseltamab

5 locations incl. Tampa

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 50

Code: NCT06369467·Phase 1·Recruiting

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A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

for Cerebral Amyloid Angiopathy

34 locations incl. Los Angeles

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 30+

Code: NCT06393712·Phase 2·Recruiting

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Boosting Resources for Tracheostomy Care at Home

for Tracheostomy

6 locations incl. La Jolla

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06283953·Enrolling By Invitation

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

for Non Hodgkin Lymphoma

5 locations incl. Stanford

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT06116110·Recruiting

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Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

for Type 2 Diabetes

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT06190158·EARLY_Phase 1·Recruiting

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PediRISE Feasibility

for Pediatric Cancer

4 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06283251·Recruiting

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A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

for Dravet Syndrome

10 locations incl. San Francisco

Sponsor: Encoded Therapeutics

Sex: All·Age: 6 Months - 17

Code: NCT05419492·Phase 1, Phase 2·Recruiting

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Study on Allopregnanolone and Depression in Women Across the Menopause Transition

for Depression

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: Female·Age: 40 - 60

Code: NCT06238700·Recruiting

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Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

65 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06309966·Phase 2, Phase 3·Recruiting

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A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

for Advanced or Metastatic Solid Tumors

14 locations incl. Phoenix

Sponsor: 858 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06395519·Phase 1, Phase 2·Recruiting

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Ergonomics in the Cardiac Catheterization Laboratory

for Ergonomics

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06506968·Recruiting

Apply to this trial