Paid Clinical Trials in Minnesota

Minnesota has 2,375 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,375 clinical trials

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Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for High Grade Epithelial Ovarian Cancer

37 locations incl. Phoenix

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05579366·Phase 1, Phase 2·Recruiting

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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

55 locations incl. Washington D.C.

Sponsor: NRG Oncology

Sex: Female·Age: 18+

Code: NCT05646316·Phase 3·Recruiting

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BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for Clinical Stage III Cutaneous Melanoma AJCC v8

Drug: Cabozantinib

222 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05136196·Phase 2·Recruiting

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Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

for Schizophrenia

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05491538·Recruiting

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RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial

for Adenocarcinoma of Lung

Drug: Durvalumab

10 locations incl. Phoenix

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT04105270·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

for Melanoma

58 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 16+

Code: NCT05538130·Phase 1·Recruiting

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An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

for Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

46 locations incl. Scottsdale

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05667493·Phase 3·Enrolling By Invitation

tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

for Obesity

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT05225233·Recruiting

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Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

for Advanced NSCLC

Drug: Adagrasib

84 locations incl. Anchorage

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05609578·Phase 2·Recruiting

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

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Study of Disrupted Sleep in Somali Americans

for Hypertension

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05411029·Recruiting

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Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma

for Localized Pancreatic Adenocarcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05518903·Phase 2·Recruiting

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A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

for Pachyonychia Congenita

1 location in New Brighton

Sponsor: Palvella Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT05643872·Phase 3·Recruiting

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

29 locations incl. Los Angeles

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting

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CIFASD 5 tDCS and Cognitive Training

for Fetal Alcohol Spectrum Disorders

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 8 - 17

Code: NCT05456321·Recruiting

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Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

for Racially/Ethnically Diverse Families From Urban Settings

2 locations incl. Athens

Sponsor: University of Colorado, Denver

Sex: All·Age: 8 - 18

Code: NCT05744973·Recruiting

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Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start

for Contraception

8 locations incl. San Jose

Sponsor: University of Utah

Sex: Female·Age: 16 - 35

Code: NCT05444582·Phase 4·Recruiting

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Enhancing the Natriuretic Peptide System in HFpEF

for Heart Failure With Preserved Ejection Fraction

1 location in Rochester

Sponsor: Horng Chen

Sex: All·Age: 18+

Code: NCT05279742·Phase 1, Phase 2·Enrolling By Invitation

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

for Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06115772·Recruiting

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Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

for AL Amyloidosis

Drug: Venetoclax

6 locations incl. Birmingham

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT05451771·Phase 1, Phase 2·Recruiting

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Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

for Parkinson's Disease Psychosis

24 locations incl. Tucson

Sponsor: VA Office of Research and Development

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT04373317·Phase 4·Recruiting

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A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for Colorectal Neoplasms

128 locations incl. Glendale

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05253651·Phase 3·Recruiting

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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for Atherosclerotic Cardiovascular Disease in Patients With ESKD

Drug: Clazakizumab

164 locations incl. Decatur

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT05485961·Phase 2, Phase 3·Recruiting

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HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

12 locations incl. La Jolla

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting

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Maternal Probiotic Supplementation for Improved Outcomes in Infants of Diabetic Mothers

for Infant of Diabetic Mother

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 21 - 45

Code: NCT05467150·Recruiting

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A Study of Optical Fusion Trans-Perineal Grid

for Prostate Biopsy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Male·Age: 45+

Code: NCT05573048·Enrolling By Invitation

Implementation of Suicide Risk Models in Health Systems

for Suicide, Attempted

3 locations incl. Detroit

Sponsor: Kaiser Permanente

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06060535·Enrolling By Invitation

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

for Recurrent B-Cell Non-Hodgkin Lymphoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04892277·Phase 1·Recruiting

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Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

for Barrett Esophagus

14 locations incl. Gilbert

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05530343·Recruiting

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting

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Natural History Study for DNA Repair Disorders

for DNA Repair Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 6 Months+

Code: NCT05484570·Recruiting

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Safety and Effectiveness of Surgeon-Modified Stent Grafts forTreatment of Complex Aortic Aneurysms

for Thoracoabdominal Aneurysm

1 location in Minneapolis

Sponsor: Jesse Manunga, MD

Sex: All·Age: 18+

Code: NCT05531084·Not Yet Recruiting

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

22 locations incl. Birmingham

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting

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A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis

for NMDAR Autoimmune Encephalitis

20 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 12+

Code: NCT05503264·Phase 3·Recruiting

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Post-Market Study to Assess iTind Safety in Comparison to UroLift

for Benign Prostatic Hyperplasia (BPH)

15 locations incl. Phoenix

Sponsor: Olympus Corporation of the Americas

Sex: Male·Age: 50+

Code: NCT04757116·Recruiting

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

for Relapsed or Refractory Multiple Myeloma

Drug: Mezigdomide

56 locations incl. Los Alamitos

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT05519085·Phase 3·Recruiting

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A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

for Lung Transplant

3 locations incl. Louisville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05547698·Recruiting

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Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology

for Fontan Palliation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05206955·Phase 3·Recruiting

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

32 locations incl. Birmingham

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting

Apply to this trial