Paid Clinical Trials in Minnesota

Minnesota has 2,375 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,375 clinical trials

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Economic and Clinical Outcomes of (Whole Exome) Sequencing in Tapestry

for Health Care Utilization

2 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05045222·Enrolling By Invitation

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for Metastatic Colorectal Cancer

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04929223·Phase 1·Recruiting

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A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

22 locations incl. Birmingham

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

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Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study

for Diffuse Midline Glioma, H3 K27M-Mutant

2 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: All·Age: 1+

Code: NCT05077735·Phase 2·Recruiting

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PCS in Severe Treatment Resistant Depression

for Treatment Resistant Depression

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22 - 70

Code: NCT04124341·Recruiting

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RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery

for Shivering

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT04730609·Phase 4·Recruiting

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Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

for Lymphoma, B-Cell

Drug: Iberdomide

17 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT04884035·Phase 1·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

for ALK Fusion-positive Solid or CNS Tumors

7 locations incl. Palo Alto

Sponsor: Hoffmann-La Roche

Sex: All·Age: Up to 17

Code: NCT04774718·Phase 1, Phase 2·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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Helix Research Network

for Genetic Predisposition to Disease

14 locations incl. Fort Wayne

Sponsor: Helix, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06057181·Recruiting

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Perform Humeral System Study

for Osteoarthritis Shoulder

6 locations incl. Lexington

Sponsor: Stryker Trauma and Extremities

Sex: All·Age: 18+

Code: NCT05067543·Recruiting

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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

11 locations incl. Washington D.C.

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

9 locations incl. San Francisco

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor

for Acute Major Bleeding

10 locations incl. Torrance

Sponsor: Octapharma

Sex: All·Age: 18+

Code: NCT04867837·Phase 3·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation

for Healthy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04880226·Recruiting

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Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities

for Breast Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06058650·Recruiting

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Backtracking Leukemia-Typical Somatic Mutations in Cord Blood

for Acute Lymphoblastic Leukemia

1 location in Minneapolis

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT05014165·Recruiting

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Improving Spinal Cord Stimulation With ECAPS

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT04938245·Recruiting

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Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

for Lymphoma, Non-Hodgkin

12 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04996706·Enrolling By Invitation

Long-Term Follow-up of Subjects Who Were Treated With ST-920

for Fabry Disease

8 locations incl. Irvine

Sponsor: Sangamo Therapeutics

Sex: All·Age: 18+

Code: NCT05039866·Enrolling By Invitation

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

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64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

for Prostatic Neoplasms, Castration-Resistant

7 locations incl. Stanford

Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male·Age: 18+

Code: NCT04868604·Phase 1, Phase 2·Recruiting

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Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma

for Mantle Cell Lymphoma

7 locations incl. New Orleans

Sponsor: Academic and Community Cancer Research United

Sex: All·Age: 18 - 75

Code: NCT04626791·Phase 2·Recruiting

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Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

24 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Shear-wave Elastography Compared to Respiratory Function Testing

for Respiratory Function Loss

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04959526·Recruiting

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Zimmer Biomet Shoulder Arthroplasty PMCF

for Shoulder Fractures

12 locations incl. Irvine

Sponsor: Zimmer Biomet

Sex: All·Age: 20+

Code: NCT04984291·Recruiting

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EFS of the CardioMech MVRS

for Mitral Regurgitation

12 locations incl. Thousand Oaks

Sponsor: CardioMech AS

Sex: All·Age: 18+

Code: NCT04820764·Recruiting

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Connect for Cancer Prevention Study (Connect)

for Cancer

10 locations incl. Denver

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT04609072·Recruiting

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Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms

for Aortic Aneurysm, Abdominal

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03446287·Recruiting

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Neuromodulation and Cognitive Training for Substance Use Disorders

for Stimulant Use

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT04426214·Recruiting

Apply to this trial