Paid Clinical Trials in Missouri

Missouri has 2,078 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,078 clinical trials

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Assessment of CCM in HF With Higher Ejection Fraction

for Heart Failure

105 locations incl. Birmingham

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT05064709·Recruiting

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A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

for Stereotypical Prolonged Seizures

53 locations incl. Phoenix

Sponsor: UCB Biopharma SRL

Sex: All·Age: 12+

Code: NCT05076617·Phase 3·Enrolling By Invitation

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

for HER2-positive Advanced Solid Tumor

Drug: DB-1303/BNT323

35 locations incl. Cerritos

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05150691·Phase 1, Phase 2·Recruiting

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

34 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting

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Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)

for Migraine

Drug: Ubrogepant

109 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05127954·Phase 3·Enrolling By Invitation

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for Migraine

Drug: Ubrogepant

125 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05125302·Phase 3·Recruiting

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

107 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting

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Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

for Lymphoplasmacytic Lymphoma

Drug: Venetoclax

133 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04840602·Phase 2·Recruiting

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Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

for Type 2 Diabetes Mellitus

79 locations incl. Huntsville

Sponsor: Prokidney

Sex: All·Age: 30 - 80

Code: NCT05099770·Phase 3·Recruiting

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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for Refractory Angina

70 locations incl. Phoenix

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT05102019·Recruiting

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

20 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting

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Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

for Solid and Hematological Malignancies

49 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: All ages

Code: NCT05041309·Enrolling By Invitation

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

for Neovascular Age-related Macular Degeneration

Drug: Ranibizumab

51 locations incl. Mesa

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT04853251·Phase 4·Recruiting

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

10 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting

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Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

20 locations incl. Birmingham

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

24 locations incl. Tucson

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting

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A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

for Stereotypical Prolonged Seizures

66 locations incl. Phoenix

Sponsor: UCB Biopharma SRL

Sex: All·Age: 12+

Code: NCT05077904·Phase 3·Recruiting

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Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma

for Oropharyngeal Squamous Cell Carcinoma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT04852328·Phase 2·Recruiting

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Extension Study of Infigratinib in Children With Achondroplasia (ACH)

for Achondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT05145010·Phase 2·Enrolling By Invitation

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

for Atrial Fibrillation

3 locations incl. Covington

Sponsor: Tulane University

Sex: All·Age: 40 - 120

Code: NCT05014802·Recruiting

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Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for Sickle Cell Disease

4 locations incl. Los Angeles

Sponsor: Kamau Therapeutics

Sex: All·Age: 12 - 40

Code: NCT04819841·Phase 1, Phase 2·Recruiting

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Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

for Renal Pelvis and Ureter Urothelial Carcinoma

Drug: Durvalumab

258 locations incl. Kingman

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04628767·Phase 2, Phase 3·Recruiting

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Decreasing Emergence Agitation With Personalized Music

for Surgical Procedure, Unspecified

2 locations incl. Stanford

Sponsor: Stanford University

Sex: All·Age: 3 - 9

Code: NCT05044832·Recruiting

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Clinical Utility of Residual Hearing in the Cochlear Implant Ear

for Hearing Loss, Sensorineural

5 locations incl. Rochester

Sponsor: Ohio State University

Sex: All·Age: 18 - 79

Code: NCT04707885·Recruiting

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Ceribell Delirium Data Collection Study

for Delirium

7 locations incl. Stanford

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT04962815·Recruiting

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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

for Breast Cancer, NOS

347 locations incl. Fairbanks

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 39

Code: NCT05108298·Recruiting

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

21 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting

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Desara ® One Single Incision Sling 522 Study

for Stress Urinary Incontinence

15 locations incl. Phoenix

Sponsor: Caldera Medical, Inc.

Sex: Female·Age: 18+

Code: NCT04772131·Recruiting

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Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach

for Obesity, Morbid

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT04841057·Enrolling By Invitation

Amygdala Memory Enhancement

for Brain Diseases

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 75

Code: NCT05065450·Recruiting

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Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

for Cardiomyopathy

21 locations incl. Little Rock

Sponsor: Tenaya Therapeutics

Sex: All·Age: 0 - 18

Code: NCT05112237·Recruiting

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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

16 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting

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Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

for Bipolar I Disorder

14 locations incl. Dothan

Sponsor: Alkermes, Inc.

Sex: All·Age: 10 - 17

Code: NCT04987229·Phase 3·Enrolling By Invitation

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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Alzheimer"s Imaging Biomarkers in Obesity

for Alzheimer Disease

1 location in St Louis

Sponsor: Cyrus A Raji

Sex: All·Age: 40 - 60·Accepts healthy volunteers

Code: NCT05077579·Recruiting

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A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for Breast Cancer

14 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05123482·Phase 1, Phase 2·Recruiting

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

22 locations incl. Birmingham

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting

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Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

11 locations incl. Birmingham

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

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