Paid Clinical Trials in Missouri

Missouri has 2,078 paid clinical trials enrolling now across cities including St Louis, Kansas City and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Missouri include Washington University School of Medicine, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,078 clinical trials

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Auricular VNS Following Subarachnoid Hemorrhage

for Subarachnoid Hemorrhage

1 location in St Louis

Sponsor: Anna Huguenard

Sex: All·Age: 18+

Code: NCT04557618·Recruiting

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Drug: Bevacizumab

603 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04181060·Phase 3·Recruiting

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

55 locations incl. Huntsville

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting

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Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

for Heart Failure With Preserved Ejection Fraction (HFpEF

20 locations incl. Birmingham

Sponsor: Axon Therapies, Inc.

Sex: All·Age: 40+

Code: NCT04592445·Recruiting

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

209 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting

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Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for Recurrent World Health Organization (WHO) Grade II Glioma

Drug: Trametinib

17 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 25

Code: NCT04485559·Phase 1·Recruiting

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Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

for Sleep Wake Disorders

11 locations incl. Los Angeles

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT04652882·Phase 3·Recruiting

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A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

for Amblyopia

68 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 3 - 13

Code: NCT04378790·Phase 3·Recruiting

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A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

for Muscular Dystrophy, Duchenne

7 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 2+

Code: NCT04626674·Phase 1·Recruiting

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

35 locations incl. Birmingham

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting

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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

12 locations incl. Birmingham

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting

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The ENCIRCLE Trial

for Mitral Regurgitation

56 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04153292·Recruiting

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A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

38 locations incl. Duarte

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT04302025·Phase 2·Recruiting

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The Tether™ - Vertebral Body Tethering System Post Approval Study

for Scoliosis Idiopathic

10 locations incl. San Diego

Sponsor: ZimVie

Sex: All·Age: All ages

Code: NCT04505579·Recruiting

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A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer

for Solid Tumor

8 locations incl. Aurora

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT04516447·Phase 1·Recruiting

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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for Supratentorial Hemorrhage

20 locations incl. Burbank

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: 18+

Code: NCT04494295·Recruiting

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NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for Aortic Dissection

31 locations incl. Birmingham

Sponsor: Endospan Ltd.

Sex: All·Age: 18+

Code: NCT04471909·Recruiting

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

177 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting

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Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

for Metastatic Castration-Resistant Prostate Carcinoma

32 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04071236·Phase 1, Phase 2·Recruiting

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Child and Adolescent Registry for Participants With Narcolepsy

for Narcolepsy

25 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: Up to 17

Code: NCT04899947·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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Lumbar Interbody Implant Study

for Degenerative Disc Disease

16 locations incl. La Jolla

Sponsor: NuVasive

Sex: All·Age: 18+

Code: NCT04418830·Enrolling By Invitation

PET Detection of CCR2 in Human Atherosclerosis

for Carotid Atherosclerosis

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT04537403·Phase 1·Recruiting

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Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients

for Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound

1 location in Kansas City

Sponsor: Children's Mercy Hospital Kansas City

Sex: All·Age: 0 Days - 22

Code: NCT04629469·Recruiting

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

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Rare and Atypical Diabetes Network

for Diabetes Mellitus

13 locations incl. Aurora

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting

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Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

for Cancer of the Head and Neck

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT04444869·Phase 2·Recruiting

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Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for Buccal Mucosa Squamous Cell Carcinoma

105 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04333537·Phase 2, Phase 3·Recruiting

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Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

for Solid Tumor

5 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: 1 - 30

Code: NCT04469530·Phase 2·Recruiting

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Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

for Insomnia Chronic

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 6 - 12

Code: NCT04545606·Recruiting

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Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism

for Hyperinsulinism

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT05088798·Phase 2·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Hydrus® Microstent New Enrollment Post-Approval Study

for Primary Open Angle Glaucoma

22 locations incl. Irvine

Sponsor: Alcon Research

Sex: All·Age: 45+

Code: NCT04553523·Recruiting

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A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

for Myelodysplastic Syndrome

49 locations incl. Birmingham

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04227847·Phase 1·Recruiting

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Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

for Ankle Fractures

1 location in Columbia

Sponsor: Kyle Schweser MD

Sex: All·Age: 18+

Code: NCT03966027·Recruiting

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A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

for Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Drug: Obrixtamig

4 locations incl. Atlanta

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT04429087·Phase 1·Recruiting

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Mindfulness in Endometrial and Cervical Cancer

for Gynecologic Cancer

1 location in St Louis

Sponsor: St. Louis University

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04512144·Recruiting

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

18 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

Apply to this trial