Breast oncology Clinical Trials in New York, NY

As of June 2026, 130 paid clinical trials are recruiting for Breast oncology in New York, New York. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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130 clinical trials for Breast oncology

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Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

for Breast Cancer

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05590949·Recruiting

Apply to this trial

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

for Breast Cancer

10 locations incl. Miami

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05570253·Phase 2·Recruiting

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Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)

for Breast Cancer

1 location in New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05561842·Recruiting

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

20 locations incl. Birmingham

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting

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A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

for Oligometastatic Breast Carcinoma

8 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05534438·Phase 2·Recruiting

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Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

for Metastatic Breast Cancer

Drug: Palazestrant

14 locations incl. Gilbert

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05508906·Phase 1·Recruiting

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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A Study of XMT-1660 in Participants With Solid Tumors

for Triple Negative Breast Cancer

26 locations incl. Phoenix

Sponsor: Mersana Therapeutics

Sex: All·Age: 18+

Code: NCT05377996·Phase 1·Recruiting

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

45 locations incl. Goodyear

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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Comprehensive Outcomes for After Cancer Health

for Ovarian Cancer

7 locations incl. Gainesville

Sponsor: Pack Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05349227·Recruiting

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A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

for Breast Cancer

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05412225·Phase 1·Recruiting

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Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

for Breast Cancer

Drug: Durvalumab

7 locations incl. Birmingham

Sponsor: Colette Shen

Sex: All·Age: 18+

Code: NCT04711824·Phase 1, Phase 2·Recruiting

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Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

for CNS Cancer

1 location in New York

Sponsor: The New York Proton Center

Sex: All·Age: 18+

Code: NCT05313191·Recruiting

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De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You

for Breast Cancer

2 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT05134779·Recruiting

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

24 locations incl. Tucson

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting

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A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

for Breast Cancer

2 locations incl. Montvale

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT05130801·Phase 1, Phase 2·Recruiting

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Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

for Breast Cancer

7 locations incl. San Francisco

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT03990896·Phase 2·Recruiting

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Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients

for Educational Materials for Genetic Testing

4 locations incl. Brooklyn

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04751435·Recruiting

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A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

for Breast Cancer

14 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05123482·Phase 1, Phase 2·Recruiting

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Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

for Breast Cancer

3 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT05095207·Phase 1, Phase 2·Recruiting

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

for Salivary Gland Tumor

3 locations incl. New York

Sponsor: Avacta Life Sciences Ltd

Sex: All·Age: 18+

Code: NCT04969835·Phase 1·Recruiting

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ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

53 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting

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Breast Elasticity Imaging During Neoadjuvant Chemotherapy

for Breast Cancer

1 location in New York

Sponsor: Columbia University

Sex: Female·Age: 18+

Code: NCT04824027·Recruiting

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A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

for Triple Negative Breast Cancer

7 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT04683679·Phase 2·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

for Breast Cancer

19 locations incl. Tucson

Sponsor: Criterium, Inc.

Sex: All·Age: All ages

Code: NCT04567420·Phase 2·Recruiting

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SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

for Pancreatic Adenocarcinoma Metastatic

2 locations incl. Boston

Sponsor: General Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04150042·Phase 1·Recruiting

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Combined Immunotherapies in Metastatic ER+ Breast Cancer

for Breast Cancer

3 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT04563507·Phase 2·Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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Opioid Dispensing Device for Post-Operative Pain in Cancer Patients

for Opioid Use

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 99

Code: NCT05585788·Recruiting

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Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study

for Breast Cancer

3 locations incl. Brooklyn

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 19 - 90

Code: NCT04371913·Recruiting

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Converting HR+ Breast Cancer Into an Individualized Vaccine

for Breast Cancer

8 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT03804944·Phase 2·Recruiting

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Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

for Invasive Ductal Breast Carcinoma

9 locations incl. Norwalk

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 45+

Code: NCT04084730·Phase 2·Recruiting

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Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease

for Triple Negative Breast Cancer

12 locations incl. San Carlos

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT03808337·Phase 2·Recruiting

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Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

for Metastatic Breast Cancer

3 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 19 - 90

Code: NCT03449238·Phase 1, Phase 2·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Talking to Employers and Medical Staff About Breast Cancer Treatment and Your Job

for Breast Cancer

9 locations incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Female·Age: 18+

Code: NCT03572374·Recruiting

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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for Metastatic Breast Cancer

16 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT03424005·Phase 1, Phase 2·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

Apply to this trial

Conditions in Breast oncology (New York, NY)

Breast cancer· 102 Metastatic breast cancer· 29 Triple-negative breast cancer· 14 HER2-negative breast cancer· 8 HER2-positive breast cancer· 7