Clinical Trials at Columbia University Irving Medical Center

As of July 2026, 163 paid clinical trials are recruiting at Columbia University Irving Medical Center, located at 622 W 168TH ST, PH 8 EAST, ROOM 101, NEW YORK, NY 10032-3720, phone (212) 305-9818 in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

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166 clinical trials at Columbia University Irving Medical Center

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

Sites in New York +15 more locations

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting·Listed Feb 2025

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RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

for Systemic Sclerosis

Sites in New York, Rochester +8 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 75

Code: NCT06328777·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in New York, Manhasset +22 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting·Listed Jun 2024

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Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

Sites in New York +13 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

Sites in New York +19 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

Sites in New York +12 more locations

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting·Listed Oct 2024

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Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

Sites in New York +14 more locations

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in New York +12 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting·Listed Mar 2025

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A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

Sites in New York, The Bronx +10 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

for Cardiomyopathy

Sites in New York, The Bronx +19 more locations

Sponsor: Tenaya Therapeutics

Sex: All·Age: 0 - 18

Code: NCT05112237·Recruiting·Listed Nov 2021

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Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

Sites in New York +17 more locations

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting·Listed Dec 2022

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A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in New York +3 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18 - 75

Code: NCT07304154·Phase 1·Recruiting·Listed Dec 2025

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A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

for Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)

Sites in New York +8 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05788536·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for Sickle Cell Disease

Sites in New York +5 more locations

Sponsor: Kamau Therapeutics

Sex: All·Age: 12 - 50

Code: NCT04819841·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

for Pancreatic Cancer, Metastatic

Sites in New York +2 more locations

Sponsor: Engeneic Pty Limited

Sex: All·Age: 18+

Code: NCT07049055·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies

for Muscular Atrophy, Spinal

Sites in New York +2 more locations

Sponsor: Biogen

Sex: Female·Age: 18 - 54

Code: NCT05789758·Recruiting·Listed Mar 2023

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

Sites in New York +7 more locations

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting·Listed Jan 2025

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A Study of ASKG915 in Patients With Selected Advanced Solid Tumors.

for Advanced Solid Tumors

Sites in New York +1 more location

Sponsor: AskGene Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05867420·Phase 1, Phase 2·Recruiting·Listed May 2023

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

Sites in New York +8 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting·Listed Apr 2025

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CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)

for T Cell Non-Hodgkin Lymphoma

Sites in New York +1 more location

Sponsor: Vittoria Biotherapeutics

Sex: All·Age: 18+

Code: NCT06420089·Phase 1·Recruiting·Listed May 2024

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A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

Sites in New York +5 more locations

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting·Listed Feb 2025

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A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

Sites in New York +13 more locations

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting·Listed Apr 2026

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TeleheartCR vs. Clinic-Based Cardiac Rehabilitation After Acute Coronary Syndrome

for Acute Coronary Syndrome (ACS)

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07541014·Recruiting·Listed Apr 2026

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Cervical Spinal Cord Associative Plasticity

for Cervical Spinal Cord Plasticity

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07539025·Recruiting·Listed Apr 2026

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rTMS for Postoperative Brain Tumor Patients

for Brain Tumors

1 location in New York

Sponsor: Brian J.Gill

Sex: All·Age: 22 - 65

Code: NCT07530536·Recruiting·Listed Apr 2026

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Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

for Chronic Heart Failure

1 location in New York

Sponsor: Melana Yuzefpolskaya, MD

Sex: All·Age: 18+

Code: NCT07490054·Phase 1·Recruiting·Listed Mar 2026

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A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women

for Mammography

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07511621·Recruiting·Listed Apr 2026

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Effect of Insulin Lowering on Lipogenesis

for Hyperinsulinemia

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 65

Code: NCT07403604·Phase 1·Recruiting·Listed Feb 2026

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Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

for HFrEF - Heart Failure With Reduced Ejection Fraction

Sites in New York +6 more locations

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07335510·Recruiting·Listed Jan 2026

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Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)

for PTSD - Post Traumatic Stress Disorder

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 81

Code: NCT07410481·Recruiting·Listed Feb 2026

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Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) and Cemiplimab for Locally Advanced Biliary Tract Cancer (BTC)

for Colon and Rectal Cancer

Drug: Cemiplimab

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07433673·Phase 2·Recruiting·Listed Feb 2026

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Gait and Bone Health in SMA

for Spinal Muscular Atrophy Type 3

1 location in New York

Sponsor: Jacqueline Montes

Sex: All·Age: 8 - 50

Code: NCT07400198·Recruiting·Listed Feb 2026

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A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients

for Depression and CVD

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07390331·Recruiting·Listed Feb 2026

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in New York, White Plains +40 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

Sites in New York +20 more locations

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting·Listed Jun 2024

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Teclistamab-Daratumumab in AL Amyloidosis

for Amyloid Light-chain Amyloidosis

Drug: Daratumumab

Sites in New York +2 more locations

Sponsor: Rajshekhar Chakraborty, MD

Sex: All·Age: 18 - 100

Code: NCT07110844·Phase 2·Recruiting·Listed Aug 2025

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Amping up With PemJAK

for Non-Hodgkin Lymphoma

1 location in New York

Sponsor: Seda S. Tolu

Sex: All·Age: 18 - 95

Code: NCT07283822·Phase 2·Recruiting·Listed Dec 2025

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Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

Sites in New York, Rochester +34 more locations

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting·Listed May 2016

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Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity

for Asthma Attack

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 7 - 18

Code: NCT07116460·Recruiting·Listed Aug 2025

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in New York, Queens +43 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

Apply to this trial