Clinical Trials at Columbia University Irving Medical Center

As of June 2026, 185 paid clinical trials are recruiting at Columbia University Irving Medical Center in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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185 clinical trials at Columbia University Irving Medical Center

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Amping up With PemJAK

for Non-Hodgkin Lymphoma

1 location in New York

Sponsor: Seda S. Tolu

Sex: All·Age: 18 - 95

Code: NCT07283822·Phase 2·Recruiting

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A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

for Metastatic Castration-resistant Prostate Cancer

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: Male·Age: 18+

Code: NCT07103018·Phase 1·Recruiting

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IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

for Scoliosis Correction

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 10 - 19

Code: NCT07217873·Phase 2, Phase 3·Recruiting

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Teclistamab-Daratumumab in AL Amyloidosis

for Amyloid Light-chain Amyloidosis

Drug: Daratumumab

1 location in New York

Sponsor: Suzanne Lentzsch, MD

Sex: All·Age: 18 - 100

Code: NCT07110844·Phase 2·Recruiting

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Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

for Lymphangioleiomyomatosis (LAM)

2 locations incl. New York

Sponsor: Columbia University

Sex: Female·Age: 18 - 64

Code: NCT06889168·Phase 1·Recruiting

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

8 locations incl. Birmingham

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting

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Anxiety During Abstinence in AUD

for Alcohol Use Disorder

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT06793488·EARLY_Phase 1·Recruiting

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Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

for Chronic Heart Failure

1 location in New York

Sponsor: Melana Yuzefpolskaya, MD

Sex: All·Age: 18+

Code: NCT07490054·Phase 1·Recruiting

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Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for PIK3CA Mutation

51 locations incl. Gilbert

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06982521·Phase 3·Recruiting

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Pivotal, Prospective, Multi-centre, Single-arm Study to Evaluate the Safety and Effectiveness of Oli for Identification of Patients, During the Intrapartum Period, Who Are at Higher Risk of Developing Abnormal Postpartum Uterine Bleeding, Including Postpartum Haemorrhage

for Post Partum Haemorrhage

5 locations incl. Denver

Sponsor: Baymatob Operations Pty Ltd

Sex: Female·Age: 18+

Code: NCT06655207·Recruiting

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Navigating Financial and Health-Related Social Needs in Adolescent and Young Adult Cancer Survivors (AYA-NAV)

for Cancer in Adolescence

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 15+·Accepts healthy volunteers

Code: NCT06950983·Recruiting

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A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

for Lupus Erythematosus, Systemic

Drug: BMS-986353

40 locations incl. Scottsdale

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07015983·Phase 2·Recruiting

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A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

13 locations incl. Phoenix

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting

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The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium

for Delirium, Postoperative

3 locations incl. Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 60+

Code: NCT06721819·Phase 3·Recruiting

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PiMZ Longitudinal Cohort (PiMZ Logic)

for Alpha 1-Antitrypsin Deficiency

5 locations incl. Birmingham

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06505603·Recruiting

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Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury

for Acute Kidney Injury

1 location in New York

Sponsor: Giuseppe Cullaro, MD

Sex: All·Age: 18 - 70

Code: NCT06937307·Phase 2·Recruiting

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

17 locations incl. Los Angeles

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

13 locations incl. Los Angeles

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting

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131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)

for Sickling Disorder Due to Hemoglobin S

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 12 - 50

Code: NCT07015684·Phase 1·Recruiting

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

9 locations incl. Los Angeles

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting

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Characterizing Perceived Physical Fatigability in Nusinersen-treated SMA

for Spinal Muscular Atrophy

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 12+

Code: NCT06955897·Recruiting

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Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

for Lymphoma

2 locations incl. Stanford

Sponsor: Jennifer Amengual

Sex: All·Age: 15+

Code: NCT06954805·Phase 2·Recruiting

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Digital Strategies to Advance Help-Seeking Aim 1 and 2

for Clinical High Risk

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 12 - 29

Code: NCT06774430·Recruiting

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

5 locations incl. Duarte

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting

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RFA for Superficial Lipomas

for Lipoma

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06903208·Recruiting

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BBO-11818 in Adult Subjects With KRAS Mutant Cancer

for Non-Small Cell Lung Cancer

16 locations incl. Los Angeles

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06917079·Phase 1·Recruiting

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Effects of Ultra Processed Food on Intestinal Energy Harvest

for Obesity and Overweight

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 25+

Code: NCT06853288·Recruiting

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

79 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting

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Discogen for Low Back Pain

for Disc Herniation

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 21 - 75

Code: NCT06611397·Recruiting

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Brodalumab in the Treatment of Immune-Related Adverse Events

for Breast Cancer

1 location in New York

Sponsor: Brian Henick, MD

Sex: All·Age: 18+

Code: NCT06673329·Phase 1·Recruiting

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Improving Neck Control in Children With Cerebral Palsy Using Robotics

for Cerebral Palsy

2 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 11 - 21·Accepts healthy volunteers

Code: NCT06533293·Recruiting

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Moms and Babies Health and Well-being

for Maternal and Child Health Outcomes

1 location in New York

Sponsor: Columbia University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06923371·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting

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Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

for Mild Cognitive Impairment (MCI)

4 locations incl. Miami

Sponsor: Columbia University

Sex: All·Age: 55 - 89

Code: NCT06601933·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)

for Muscle-invasive Urothelial Carcinoma

Drug: Nivolumab

26 locations incl. Springdale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06534983·Phase 2·Recruiting

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Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

for Cervical Spinal Cord Injury

2 locations incl. New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06701422·Recruiting

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Engaging Patients in Adherence Interventions Using Behavioral Science

for Uncontrolled Hypertension

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT06543394·Enrolling By Invitation

A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

12 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting

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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

19 locations incl. Duarte

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting

Apply to this trial