Paid Clinical Trials in Ohio

Ohio has 3,485 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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3,485 clinical trials

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

25 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting

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A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

10 locations incl. Little Rock

Sponsor: Insmed Gene Therapy LLC

Sex: Male·Age: 2 - 4

Code: NCT06817382·Phase 1·Recruiting

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Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

for Neoadjuvant Treatment

2 locations incl. Cleveland

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06959511·Phase 2·Recruiting

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

Drug: Empagliflozin

216 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

54 locations incl. Scottsdale

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting

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Gender Affirming Vaginoplasty With Tubularized Augmented Peritoneal Cap (TAPCap) Utilizing Fish Skin Xenograft (Kerecis™)

for Gender Dysphoria, Adult

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Male·Age: 19 - 99

Code: NCT07286123·Recruiting

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A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

for Prostatic Neoplasms

1 location in Cleveland

Sponsor: Bayer

Sex: Male·Age: 18+

Code: NCT07406282·Recruiting

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A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

for Ovarian Cancer

14 locations incl. Augusta

Sponsor: Compugen Ltd

Sex: Female·Age: 18+

Code: NCT06888921·Phase 1, Phase 2·Recruiting

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Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

for Pancreatic Neuroendocrine Tumor (pNET)

39 locations incl. Birmingham

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06943755·Phase 2, Phase 3·Recruiting

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A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

for Breast Neoplasms

33 locations incl. Daphne

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07060807·Phase 3·Recruiting

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Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

for Major Depressive Disorder

19 locations incl. Phoenix

Sponsor: Cybin IRL Limited

Sex: All·Age: 18 - 85

Code: NCT06605105·Phase 3·Enrolling By Invitation

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

for Bipolar Disorder Type I With Mania

Drug: KarXT

52 locations incl. Glendale

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT06929273·Phase 3·Recruiting

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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

18 locations incl. Arcadia

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting

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Curcumin & Astaxanthin for Lowering Triglyceride Readings and Inflammation

for Triglycerides

1 location in Dublin

Sponsor: Medinutra LLC

Sex: All·Age: 21 - 59·Accepts healthy volunteers

Code: NCT07063056·Recruiting

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A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

for Metastatic Colorectal Cancer

4 locations incl. New Haven

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07079631·Phase 1, Phase 2·Recruiting

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Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for Non-small Cell Lung Cancer

22 locations incl. Glendale

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06765109·Phase 3·Recruiting

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Positive Processes and Transition to Health - Single-Session (PATH-SS)

for PTSD

1 location in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 18 - 65

Code: NCT06900712·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

56 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting

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A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors

for Recurrent or Metastatic Solid Tumors

6 locations incl. Newport Beach

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07015697·Phase 1·Recruiting

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A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease

for Idiopathic Parkinson´s Disease

3 locations incl. Tucson

Sponsor: Kenai Therapeutics

Sex: All·Age: 45 - 75

Code: NCT07106021·Phase 1, Phase 2·Recruiting

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Mechanisms for Laser-Induced Rejuvenation

for Skin Cancer

1 location in Fairborn

Sponsor: Wright State University

Sex: All·Age: 18+

Code: NCT06489301·Recruiting

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A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

for Systemic Lupus Erythematosus

Drug: Inebilizumab

17 locations incl. Scottsdale

Sponsor: Amgen

Sex: All·Age: 18 - 75

Code: NCT06570798·Phase 2·Recruiting

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

55 locations incl. Phoenix

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for Colon Adenocarcinoma

Drug: Calderasib

27 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06997497·Phase 3·Recruiting

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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

for Alzheimer Disease

Drug: KarXT

39 locations incl. Chandler

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT07011745·Phase 3·Recruiting

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Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes

for Renal Impairment After Cardiac Surgery

4 locations incl. Weston

Sponsor: 3ive Labs

Sex: All·Age: 22 - 85

Code: NCT07017933·Recruiting

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A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

for Early Alzheimer's Disease

36 locations incl. Irvine

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 50 - 85

Code: NCT07033494·Phase 2·Recruiting

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

18 locations incl. Birmingham

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting

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Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

for Relapsed CLL

1 location in Cleveland

Sponsor: Paolo Caimi, MD

Sex: All·Age: 18+

Code: NCT06916767·Phase 1·Recruiting

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A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

for Kidney Disease

40 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06963827·Phase 3·Recruiting

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Comprehensive Assessment of Reactions to Pharmacogenetics in Complex Care Patients

for Pediatric Medical Complexity Based on PMCA Score of 3

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT07060300·Enrolling By Invitation

A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis (AD)

48 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07105488·Phase 2·Recruiting

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HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

for Heart Defects, Congenital

2 locations incl. Los Angeles

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+

Code: NCT06175104·Recruiting

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Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer

for Metastatic Prostate Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 19+

Code: NCT06738303·Phase 2·Recruiting

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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

37 locations incl. Irvine

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

for Alzheimer's Disease

Drug: KarXT

28 locations incl. Long Beach

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 60 - 85

Code: NCT06976216·Phase 3·Recruiting

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Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

for Atopic Dermatitis

Drug: Nemolizumab

59 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 12+

Code: NCT06988605·Recruiting

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

65 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting

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A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

for Lupus Erythematosus, Systemic

Drug: BMS-986353

40 locations incl. Scottsdale

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 16+

Code: NCT07015983·Phase 2·Recruiting

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Literacy Instruction Through Media for Everyone

for Media Effects on Literacy Gains in Young Children

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 42 Months - 57 Months·Accepts healthy volunteers

Code: NCT06796790·Recruiting

Apply to this trial