Paid Clinical Trials in Ohio

Ohio has 3,485 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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3,485 clinical trials

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A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Solid Tumors

11 locations incl. Birmingham

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06760819·Phase 2·Recruiting

Apply to this trial

MOTION Clinical Trial

for Osteoarthritis, Knee

8 locations incl. Davis

Sponsor: Moximed

Sex: All·Age: All ages

Code: NCT06843980·Recruiting

Apply to this trial

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

for Bacterial Infection

10 locations incl. Torrance

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06709521·Phase 4·Recruiting

Apply to this trial

Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants

for Obesity and Overweight

Drug: Tirzepatide

20 locations incl. Bessemer

Sponsor: Gan and Lee Pharmaceuticals, USA

Sex: All·Age: 18 - 75

Code: NCT06737042·Phase 2·Not Yet Recruiting

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

for Parkinson Disease

27 locations incl. Phoenix

Sponsor: Impax Laboratories, LLC

Sex: All·Age: 18+

Code: NCT06765668·Phase 4·Recruiting

Apply to this trial

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 location in Athens

Sponsor: Ohio University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06828926·Recruiting

Apply to this trial

EEG-based Personalized Transcranial Magnetic Stimulation (eTMS) to Treat Post-Traumatic Stress Disorder

for Stress Disorder, Post Traumatic

2 locations incl. Dayton

Sponsor: Wave Neuroscience

Sex: All·Age: 22 - 65

Code: NCT06892028·Recruiting

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Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery

for Bleeding

1 location in Cleveland

Sponsor: Kristen Ban

Sex: All·Age: 18 - 100

Code: NCT06657924·Phase 2·Recruiting

Apply to this trial

Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities

for Stroke

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07092293·Recruiting

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A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

Drug: Nipocalimab

12 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting

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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

for Neurofibromatosis Type 1

14 locations incl. Birmingham

Sponsor: Healx Limited

Sex: All·Age: 12+

Code: NCT06541847·Phase 2·Recruiting

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This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

for Peripheral Nerve Injury Upper Limb

18 locations incl. Orlando

Sponsor: Neuraptive Therapeutics Inc.

Sex: All·Age: 18 - 80

Code: NCT06616025·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

for Chronic Inflammatory Demyelinating Polyneuropathy

31 locations incl. Birmingham

Sponsor: Dianthus Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06858579·Phase 3·Recruiting

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A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: Remibrutinib

24 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06744920·Phase 3·Recruiting

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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for mCRPC (Metastatic Castration-resistant Prostate Cancer)

18 locations incl. Fountain Valley

Sponsor: Pathos AI, Inc.

Sex: Male·Age: 18+

Code: NCT06785636·Phase 1, Phase 2·Recruiting

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A Study of TAK-360 in Adults With Idiopathic Hypersomnia

for Idiopathic Hypersomnia

13 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06812078·Phase 2·Recruiting

Apply to this trial

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for Castration-Resistant Prostate Carcinoma

107 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632977·Phase 2·Recruiting

Apply to this trial

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

71 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting

Apply to this trial

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

for Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)

25 locations incl. Fairhope

Sponsor: Cytokinetics

Sex: All·Age: 40 - 85

Code: NCT06793371·Phase 2·Recruiting

Apply to this trial

Targeting Aging With a Ketone Ester for Function in Frailty

for Frail Elderly

3 locations incl. Novato

Sponsor: Buck Institute for Research on Aging

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06645847·Recruiting

Apply to this trial

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

Apply to this trial

North American Comfilcon A Clinical Study

for Astigmatism

4 locations incl. Berkeley

Sponsor: CooperVision International Limited (CVIL)

Sex: All·Age: 8 - 75

Code: NCT06902584·Recruiting

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

19 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting

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A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for Lung Cancer

14 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06618287·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

19 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

Apply to this trial

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

for Chronic Lymphocytic Leukaemia

3 locations incl. Charlotte

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06651970·Phase 4·Recruiting

Apply to this trial

BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

for AML, Adult Recurrent

6 locations incl. Duarte

Sponsor: BlueSphere Bio, Inc

Sex: All·Age: 18 - 70

Code: NCT06704152·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for KRAS G12C Mutation

11 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06720987·Phase 1·Recruiting

Apply to this trial

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

for Rotator Cuff Tears

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06733480·Recruiting

Apply to this trial

Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models

for Autism Spectrum Disorder

2 locations incl. Brookline

Sponsor: Psyrin Inc.

Sex: All·Age: 13 - 60

Code: NCT06792175·Enrolling By Invitation

Perioperative Sleep Quality and Postoperative Pain Outcomes

for Surgery

1 location in Columbus

Sponsor: Grant Heydinger

Sex: All·Age: 10 - 18

Code: NCT06054802·Enrolling By Invitation

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

for Anemia, Sickle Cell

4 locations incl. Wilmington

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 21

Code: NCT06290401·Recruiting

Apply to this trial

Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

34 locations incl. Birmingham

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting

Apply to this trial

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

Apply to this trial

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

32 locations incl. Tucson

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting

Apply to this trial

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

for Gastrointestinal Stromal Tumors

5 locations incl. Ann Arbor

Sponsor: Novelty Nobility, Inc.

Sex: All·Age: 18+

Code: NCT06805825·Phase 1·Recruiting

Apply to this trial

Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

for Postoperative Urinary Retention (POUR)

1 location in Cincinnati

Sponsor: TriHealth Inc.

Sex: Female·Age: 18+

Code: NCT06843538·Phase 3·Recruiting

Apply to this trial

Study of Olutasidenib and Temozolomide in HGG

for High Grade Glioma

11 locations incl. Aurora

Sponsor: Rigel Pharmaceuticals

Sex: All·Age: 12 - 39

Code: NCT06161974·Phase 2·Recruiting

Apply to this trial

Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)

for Pyoderma Gangrenosum

Drug: Guselkumab

2 locations incl. Columbus

Sponsor: Oregon Health and Science University

Sex: All·Age: 18 - 99

Code: NCT06563323·Phase 2·Recruiting

Apply to this trial

Juveena Hydrogel System Feasibility Study for Heavy Menstrual Bleeding (HMB)

for Heavy Menstrual Bleeding

4 locations incl. Phoenix

Sponsor: Rejoni Inc.

Sex: Female·Age: 18 - 45

Code: NCT06634719·Recruiting

Apply to this trial