Paid Clinical Trials in Ohio

Ohio has 3,488 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,488 clinical trials

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Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

for Benign Prostatic Hyperplasia With Outflow Obstruction

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: Male·Age: 18+

Code: NCT06179654·Recruiting

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Evaluation of the GORE® Ascending Stent Graft

for Aortic Aneurysm, Thoracic

41 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05800743·Enrolling By Invitation

Prehospital Analgesia INtervention Trial (PAIN)

for Traumatic Injury

11 locations incl. San Diego

Sponsor: Jason Sperry

Sex: All·Age: 18+

Code: NCT05437575·Phase 3·Recruiting

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Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

for Spinal Muscular Atrophy

15 locations incl. Phoenix

Sponsor: Alcyone Therapeutics, Inc

Sex: All·Age: 3+

Code: NCT05866419·Recruiting

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

for Locally Advanced Solid Tumors

Drug: Atezolizumab

6 locations incl. Birmingham

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06031441·Phase 1·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

539 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

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A Multicenter Multinational Observational Study of Children With Hypochondroplasia

for Hypochondroplasia

16 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: Up to 15

Code: NCT06212947·Recruiting

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Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

for Lymphatic Malformations

16 locations incl. Oakland

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT05948943·Phase 2, Phase 3·Recruiting

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

for Breast Cancer

Drug: Durvalumab

64 locations incl. Daphne

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06103864·Phase 3·Recruiting

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Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue

for Aortic Aneurysm

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06789809·Recruiting

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

32 locations incl. Newport Beach

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting

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A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

for Influenza

28 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Weeks - 11

Code: NCT06094010·Phase 3·Recruiting

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Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up

for Hip Disease

1 location in Cleveland

Sponsor: Signature Orthopaedics

Sex: All·Age: 18 - 75

Code: NCT06153940·Recruiting

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Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

for Locally Advanced Cholangiocarcinoma

4 locations incl. San Francisco

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06160752·Phase 1·Recruiting

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Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma

for Lymphoma, Non-Hodgkin Lymphoma, B-Cell

2 locations incl. Cleveland

Sponsor: Luminary Therapeutics

Sex: All·Age: 18+

Code: NCT05312801·Phase 1·Recruiting

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MRI in Transcatheter Aortic Valve Replacement Patients

for Aortic Valve Stenosis

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 105

Code: NCT05603026·Recruiting

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

24 locations incl. Palo Alto

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting

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Suicide Prevention for Substance Using Youth Experiencing Homelessness

for Suicide Prevention

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 15 - 24·Accepts healthy volunteers

Code: NCT05994612·Recruiting

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Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for Non-muscle-invasive Bladder Cancer

9 locations incl. West Haven

Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT05796375·Phase 2·Recruiting

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

22 locations incl. Santa Monica

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting

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The PEERLESS II Study

for Pulmonary Embolism

50 locations incl. Birmingham

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06055920·Recruiting

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A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for Obesity

49 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06143956·Phase 2·Recruiting

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

47 locations incl. Tucson

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06016738·Phase 3·Recruiting

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Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

for Limited-stage Small Cell Lung Cancer (LS-SCLC)

29 locations incl. Goodyear

Sponsor: Shanghai Junshi Bioscience Co., Ltd.

Sex: All·Age: 18+

Code: NCT06095583·Phase 3·Recruiting

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

5 locations incl. Aurora

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting

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Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

for Sciatica Acute

24 locations incl. Auburn

Sponsor: Primus Pharmaceuticals

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06157177·Phase 4·Recruiting

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ACP-204 in Adults With Alzheimer's Disease Psychosis

for Alzheimer's Disease Psychosis

45 locations incl. Chandler

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 95

Code: NCT06159673·Phase 2, Phase 3·Recruiting

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A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)

for X-Linked Retinitis Pigmentosa

7 locations incl. Jacksonville

Sponsor: Beacon Therapeutics

Sex: Male·Age: 12+

Code: NCT06275620·Phase 2·Enrolling By Invitation

Inspiratory Muscle Training in Obese Breast Cancer Survivors

for Cancer Survivors

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female·Age: 18+

Code: NCT05193149·Recruiting

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A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)

for Cytomegalovirus (CMV)

8 locations incl. Wilmington

Sponsor: Takeda

Sex: All·Age: Up to 17

Code: NCT05319353·Phase 3·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

17 locations incl. Birmingham

Sponsor: Xentria, Inc.

Sex: All·Age: 18 - 80

Code: NCT05890729·Phase 1, Phase 2·Recruiting

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Speech-in-noise Perception in Autism and Fragile X

for Autism Spectrum Disorder

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 15 - 35·Accepts healthy volunteers

Code: NCT06088589·Recruiting

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Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

for Neovascular Age-related Macular Degeneration

63 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05904028·Phase 3·Recruiting

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for Metastatic Colorectal Carcinoma

22 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05803382·Phase 1·Recruiting

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Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure

31 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40 - 85

Code: NCT06122779·Phase 2·Recruiting

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

29 locations incl. Chandler

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

34 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting

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Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

for Anxiety

3 locations incl. Tallahassee

Sponsor: Florida State University

Sex: All·Age: 60+

Code: NCT05748613·Recruiting

Apply to this trial