Paid Clinical Trials in Ohio

Ohio has 3,488 paid clinical trials enrolling now across cities including Columbus, Cleveland and Cincinnati. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Ohio include Cleveland Clinic, Ohio State Wexner Medical Center and Cincinnati Children's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,488 clinical trials

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Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

40 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting

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Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

for Solid Tumor, Adult

4 locations incl. Detroit

Sponsor: Sairopa B.V.

Sex: All·Age: 18+

Code: NCT05856981·Phase 1·Recruiting

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Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

for Sickle Cell Trait

10 locations incl. Birmingham

Sponsor: National Alliance for Sickle Cell Centers

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06071377·Recruiting

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A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

127 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05774951·Phase 3·Recruiting

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Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

Drug: Lifileucel

22 locations incl. Birmingham

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting

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Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for T-Cell Neoplasm

Drug: Pacritinib

6 locations incl. Duarte

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT04858256·Phase 2·Recruiting

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Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

for Breast Cancer

15 locations incl. Orlando

Sponsor: Incyclix Bio

Sex: All·Age: 18+

Code: NCT05735080·Phase 1, Phase 2·Recruiting

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Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis

for Cystic Fibrosis

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06163482·EARLY_Phase 1·Recruiting

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Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

for Hematopoietic and Lymphoid Cell Neoplasm

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05178472·Recruiting

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

21 locations incl. Birmingham

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting

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A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for Geographic Atrophy

15 locations incl. Beverly Hills

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT05626114·Phase 2·Recruiting

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Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder

for Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder

Drug: Tafasitamab

4 locations incl. New Brunswick

Sponsor: Timothy Voorhees

Sex: All·Age: 18+

Code: NCT05786040·Phase 2·Recruiting

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

11 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting

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Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury

for Fecal Incontinence

1 location in Cleveland

Sponsor: MetroHealth Medical Center

Sex: All·Age: 18+

Code: NCT05626816·Recruiting

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A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

26 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05650632·Phase 1·Recruiting

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Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for Recurrent Glioblastoma, IDH-Wildtype

Drug: Selinexor

36 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05432804·Phase 1, Phase 2·Recruiting

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TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

for Breast Cancer

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 65+

Code: NCT05535192·Recruiting

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G7 Dual Mobility With Vivacit-E or Longevity PMCF

for Hip Osteoarthritis

6 locations incl. Little Rock

Sponsor: Zimmer Biomet

Sex: All·Age: 18 - 80

Code: NCT05548972·Enrolling By Invitation

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

for Growth Hormone Deficiency

27 locations incl. Phoenix

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: 1 - 18

Code: NCT05775523·Recruiting

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A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

for Growth Hormone Deficiency

27 locations incl. Phoenix

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: All ages

Code: NCT05820672·Recruiting

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Impact of 4PCP on Practitioner and Patient Outcomes

for Chronic Pain

4 locations incl. Cleveland

Sponsor: Virginia Commonwealth University

Sex: All·Age: 14 - 80

Code: NCT05580419·Recruiting

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Observational Study Protocol: LIVER-R

for Hepatobiliary Cancers

21 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06252753·Recruiting

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A Study of PYX-201 in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Scottsdale

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT05720117·Phase 1·Recruiting

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OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers

for Marginal Ulcer

1 location in Cleveland

Sponsor: Stephen Firkins

Sex: All·Age: All ages

Code: NCT05799105·Phase 4·Recruiting

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A Study of ASP1002 in Adults for Treatment of Solid Tumors

for Advanced Solid Tumors

15 locations incl. New Haven

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05719558·Phase 1·Recruiting

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3D Printed Models for Mandibular Fracture Repair

for Mandible Fracture

2 locations incl. Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18 - 80

Code: NCT05733221·Enrolling By Invitation

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

for Relapsed Sarcomas

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05210374·Phase 1·Recruiting

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A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

15 locations incl. La Mesa

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting

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A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 Months - 18

Code: NCT05735483·Phase 3·Enrolling By Invitation

Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer

for Metastatic Cancer

1 location in Cleveland

Sponsor: Roberto Vargas

Sex: All·Age: 18+

Code: NCT05065736·EARLY_Phase 1·Recruiting

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

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Tegavivint for Treating Patients With Relapsed or Refractory Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type

1 location in Columbus

Sponsor: Lapo Alinari

Sex: All·Age: 18+

Code: NCT05755087·Phase 1·Recruiting

Apply to this trial

iMmune SignAtures and Clinical outComes in AP

for Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18 - 75

Code: NCT05878236·Recruiting

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

177 locations incl. Charlottesville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study

for Venous Thromboses

27 locations incl. Stanford

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05489588·Recruiting

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Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).

for Mechanical Ventilation Complication

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18 - 110

Code: NCT05412810·Recruiting

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Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: Female·Age: 18+

Code: NCT05417308·EARLY_Phase 1·Recruiting

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Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

for Clinical Stage IV Cutaneous Melanoma AJCC v8

1 location in Columbus

Sponsor: Kari Kendra

Sex: All·Age: 18+

Code: NCT05588453·Phase 1, Phase 2·Recruiting

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Longitudinal Study for Central Nervous System Vasculitis

for Central Nervous System Vasculitis

4 locations incl. Rochester

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05734404·Recruiting

Apply to this trial