Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

for Metabolic Disease

2 locations incl. Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100·Accepts healthy volunteers

Code: NCT02890342·Recruiting

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

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Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

for Metastatic Castration-Resistant Prostate Cancer

7 locations incl. Aurora

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT02861573·Phase 1, Phase 2·Recruiting

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Late Onset Alzheimer's Disease

for Alzheimer Disease

12 locations incl. Washington D.C.

Sponsor: Columbia University

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT05010603·Recruiting

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International Registry for Patients With Castleman Disease

for Castleman Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT02817997·Recruiting

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ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

for Mycosis Fungoides

7 locations incl. Duarte

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT02848274·Recruiting

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Amish/Mennonite Research Contact Registry

for All

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02990572·Recruiting

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MEASuRE: Metreleptin Effectiveness And Safety Registry

for Generalised Lipodystrophy

16 locations incl. Birmingham

Sponsor: Amryt Pharma

Sex: All·Age: All ages

Code: NCT02325674·Recruiting

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Exome and Genome Analysis to Elucidate Genetic Etiologies and Population Characteristics in the Plain Community

for Undiagnosed Disease

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 100·Accepts healthy volunteers

Code: NCT02927158·Recruiting

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PET Tau - Neurodegenerative Disease Imaging

for Neurodegenerative Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT03143374·Phase 2, Phase 3·Recruiting

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Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma

for Anaplastic (Malignant) Meningioma

Drug: Bevacizumab

8 locations incl. Santa Monica

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT02847559·Phase 2·Recruiting

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A Registry Study of Breast Microseed Treatment

for Breast Neoplasms

3 locations incl. Pittsburgh

Sponsor: Concure Oncology-Breast Microseed Inc.

Sex: Female·Age: 50+

Code: NCT02701244·Recruiting

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Mapping Disease Pathways for Biliary Atresia

for Biliary Atresia

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03273049·Recruiting

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COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for Complex Congenital Heart Defect

25 locations incl. Little Rock

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT02744677·Recruiting

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Prospective Research Rare Kidney Stones (ProRKS)

for Hyperoxaluria

8 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT02780297·Recruiting

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

40 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting

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PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT02732171·Recruiting

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Autoimmune Blistering Diseases Study

for Pemphigus Vulgaris

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02753777·Recruiting

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Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

for MPS IIIA

2 locations incl. Columbus

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: All ages

Code: NCT02716246·Phase 2, Phase 3·Recruiting

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Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

for Community-acquired Pneumonia, Influenza, COVID-19

11 locations incl. Jacksonville

Sponsor: UMC Utrecht

Sex: All·Age: 18+

Code: NCT02735707·Phase 3·Recruiting

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MyPaTH Story Booth

for Narrative Medicine

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 99

Code: NCT03494075·Recruiting

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

174 locations incl. Birmingham

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting

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Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

for Langerhans Cell Histiocytosis

11 locations incl. Palo Alto

Sponsor: Baylor College of Medicine

Sex: All·Age: Up to 21

Code: NCT02670707·Phase 3·Recruiting

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Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute Leukemia

for Acute Leukemia

3 locations incl. Hartford

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18 - 80

Code: NCT02677064·Recruiting

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Neuroblastoma Maintenance Therapy Trial

for Neuroblastoma

42 locations incl. Birmingham

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 30

Code: NCT02679144·Phase 2·Recruiting

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A Clinical Registry of Orthobiologics Procedures

for Orthopedic Disorder

30 locations incl. Phoenix

Sponsor: Regenexx, LLC

Sex: All·Age: All ages

Code: NCT03011398·Enrolling By Invitation

Improving the Quality of Care for Adults With Inflammatory Bowel Disease

for Crohn's Disease

29 locations incl. Los Angeles

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18 - 99

Code: NCT02791854·Enrolling By Invitation

Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

4 locations incl. Los Angeles

Sponsor: Debra Weese-Mayer

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

24 locations incl. Birmingham

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting

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Evaluation of Outcome Metrics in Alexander Disease

for Alexander Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02714764·Recruiting

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Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

for Suspected Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT02637934·Phase 1·Recruiting

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Fecal Microbiome Transplant

for Clostridium Difficile

1 location in Philadelphia

Sponsor: Judith Kelsen

Sex: All·Age: 3 - 21

Code: NCT02636517·Phase 1·Enrolling By Invitation

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

for Neurofibromatosis 1

6 locations incl. Washington D.C.

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT02544022·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

for Acute Lymphoblastic Leukemia

11 locations incl. Los Angeles

Sponsor: Michael Pulsipher

Sex: All·Age: Up to 21

Code: NCT02646839·Phase 2·Enrolling By Invitation

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

52 locations incl. Phoenix

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting

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Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for Neuroblastoma

24 locations incl. Birmingham

Sponsor: Giselle Sholler

Sex: All·Age: Up to 22

Code: NCT02559778·Phase 2·Recruiting

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Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies

for Pyruvate Dehydrogenase Complex Deficiency Disease

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03056794·Recruiting

Apply to this trial