Paid Clinical Trials in South Carolina

South Carolina has 1,283 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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1,283 clinical trials

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

45 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting

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Electrical DN as an Adjunct to Eccentric Exercise, Stretching + MT for Achilles Tendinopathy

for Achilles Tendinopathy

1 location in Columbia

Sponsor: Alabama Physical Therapy & Acupuncture

Sex: All·Age: 18+

Code: NCT03968614·Recruiting

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Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

577 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting

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A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

for Bronchopulmonary Dysplasia

26 locations incl. Little Rock

Sponsor: OHB Neonatology Ltd.

Sex: All·Age: 0 Hours - 24 Hours

Code: NCT03253263·Phase 2·Recruiting

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An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

for Hyperkalaemia

14 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 0 - 18

Code: NCT03813407·Phase 3·Recruiting

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Preventing Alzheimer's With Cognitive Training

for Age-related Cognitive Decline

7 locations incl. Gainesville

Sponsor: University of South Florida

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT03848312·Phase 3·Recruiting

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

1229 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting

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Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

for Pleural Effusion

5 locations incl. Arlington Heights

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03831386·Recruiting

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A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

for Knee Arthroplasty, Total

5 locations incl. Aurora

Sponsor: Exactech

Sex: All·Age: 18+

Code: NCT05653102·Recruiting

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Anesthetics and Analgesics in Children

for Anesthesia

11 locations incl. Stanford

Sponsor: Chi Dang Hornik

Sex: All·Age: 0 - 17

Code: NCT03427736·Recruiting

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Pulmonary Hemodynamics During Exercise - Research Network

for Pulmonary Circulation Diseases

8 locations incl. Phoenix

Sponsor: Medical University of Graz

Sex: All·Age: 18+

Code: NCT03954574·Recruiting

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IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

for Ventricular Arrhythmia

34 locations incl. Phoenix

Sponsor: University of California, Los Angeles

Sex: All·Age: All ages

Code: NCT04520347·Enrolling By Invitation

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Prevent Cancer- Greenville

for Cancer

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04947098·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

334 locations incl. Gilbert

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting

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Extension Study for the Port Delivery System With Ranibizumab (Portal)

for Neovascular Age-Related Macular Degeneration

Drug: Ranibizumab

81 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50+

Code: NCT03683251·Phase 3·Recruiting

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

709 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting

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Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

15 locations incl. San Francisco

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

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Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

for Metastatic Urothelial Cancer

37 locations incl. Tucson

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT03547973·Phase 2·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

Drug: Mevrometostat

46 locations incl. Tucson

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT03460977·Phase 1·Recruiting

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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

for Locally Advanced Pancreatic Cancer

36 locations incl. Loma Linda

Sponsor: RenovoRx

Sex: All·Age: 18+

Code: NCT03257033·Phase 3·Recruiting

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Accelerated iTBS for Post Partum Depression

for Post Partum Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18 - 50

Code: NCT03417960·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

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Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation

for Paroxysmal Atrial Fibrillation

64 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT04088071·Recruiting

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A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

for Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)

Drug: Rituximab

40 locations incl. Duarte

Sponsor: Pierre Fabre Medicament

Sex: All·Age: All ages

Code: NCT03394365·Phase 3·Recruiting

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S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for Cardiotoxicity

577 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03418961·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia

455 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18 - 39

Code: NCT03150693·Phase 3·Recruiting

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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

for Grade 2 Meningioma

197 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03180268·Phase 3·Recruiting

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RCT of Olanzapine for Control of CIV in Children Receiving Highly Emetogenic Chemotherapy

for Vomiting in Infants and/or Children

6 locations incl. San Francisco

Sponsor: The Hospital for Sick Children

Sex: All·Age: 30 Months - 18

Code: NCT03118986·Phase 2·Recruiting

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Systemic Hypothermia in Acute Cervical Spinal Cord Injury

for Spinal Cord Injury, Acute

7 locations incl. Phoenix

Sponsor: University of Miami

Sex: All·Age: 18 - 70

Code: NCT02991690·Recruiting

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

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Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

156 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 21

Code: NCT02981628·Phase 2·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

for Breast Cancer

130 locations incl. Birmingham

Sponsor: Agendia

Sex: All·Age: 18+

Code: NCT03053193·Recruiting

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MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

for Lumbar Spinal Stenosis

2306 locations incl. Athens

Sponsor: Stryker Instruments

Sex: All·Age: 18+

Code: NCT03072927·Recruiting

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