Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapsefor Acute Myeloid Leukemia1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06928662·Phase 1, Phase 2·Recruiting·Listed Apr 2025Apply to this trial
Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Diseasefor Chronic Graft Versus Host DiseaseSites in Seattle +4 more locationsSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT05996627·Phase 2·Recruiting·Listed Aug 2023Apply to this trial
[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancerfor Anatomic Stage IV Breast Cancer AJCC v81 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06502691·Phase 1, Phase 2·Recruiting·Listed Jul 2024Apply to this trial
Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancerfor Anatomic Stage I Breast Cancer AJCC v81 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT04329065·Phase 2·Recruiting·Listed Apr 2020Apply to this trial
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplantfor Juvenile Myelomonocytic Leukemia1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: Up to 80Code: NCT03326921·Phase 1·Recruiting·Listed Oct 2017Apply to this trial
Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trialfor Recurrent Chronic Lymphocytic LeukemiaDrug: Venetoclax1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT04941716·Phase 2·Recruiting·Listed Jun 2021Apply to this trial
A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancerfor Anatomic Stage IV Breast Cancer AJCC v81 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT07112053·Phase 2·Recruiting·Listed Aug 2025Apply to this trial
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Studyfor Prostate CarcinomaSites in Seattle +6 more locationsSponsor: University of WashingtonSex: Male·Age: 40+·Accepts healthy volunteersCode: NCT04472338·Recruiting·Listed Jul 2020Apply to this trial
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplantfor Acute Biphenotypic LeukemiaSites in Seattle +8 more locationsSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 6 Months - 26·Accepts healthy volunteersCode: NCT03779854·Phase 2·Recruiting·Listed Dec 2018Apply to this trial
Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-Tfor Recurrent Diffuse Large B-Cell LymphomaDrug: Odronextamab1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06784726·Phase 2·Recruiting·Listed Jan 2025Apply to this trial
A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancerfor Anatomic Stage IV Breast Cancer AJCC v81 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT07078604·Phase 2·Recruiting·Listed Jul 2025Apply to this trial
Sustained Oral Fiber Supplementation for Patients Undergoing Donor Stem Cell Transplantation for Hematological Malignanciesfor Hematopoietic and Lymphatic System Neoplasm1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT04829136·Recruiting·Listed Apr 2021Apply to this trial
Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant for Patients With Accelerated and Blast Phase Myeloproliferative Neoplasmsfor Accelerated Phase Myeloproliferative NeoplasmDrug: Pacritinib1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT07148947·Phase 2·Recruiting·Listed Aug 2025Apply to this trial
Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphomafor Chronic Lymphocytic LeukemiaDrug: Sonrotoclax1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT06839053·Phase 2·Recruiting·Listed Feb 2025Apply to this trial
Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivorsfor Stage II Colorectal Cancer AJCC v81 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18 - 70Code: NCT05930496·Recruiting·Listed Jul 2023Apply to this trial
Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Studyfor Recurrent Fallopian Tube Carcinoma1 location in SeattleSponsor: University of WashingtonSex: All·Age: All agesCode: NCT06295965·Recruiting·Listed Mar 2024Apply to this trial
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasmsfor Acute Biphenotypic LeukemiaDrug: Venetoclax1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT04797767·Phase 1, Phase 2·Recruiting·Listed Mar 2021Apply to this trial
Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancerfor Anatomic Stage III Breast Cancer AJCC v8Sites in Seattle +1 more locationSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06179303·Phase 2·Recruiting·Listed Dec 2023Apply to this trial
Axatilimab for Sclerotic Chronic Graft-versus-Host Diseasefor Chronic Graft Versus Host DiseaseSites in Seattle +2 more locationsSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT07011810·Phase 2·Recruiting·Listed Jun 2025Apply to this trial
Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasmsfor Acute Myeloid LeukemiaDrug: Ruxolitinib1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT04282187·Phase 2·Recruiting·Listed Feb 2020Apply to this trial
Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphomafor Ann Arbor Stage II Follicular LymphomaDrug: Mosunetuzumab1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06442475·Phase 2·Recruiting·Listed Jun 2024Apply to this trial
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)for Acute LeukemiaSites in Seattle +2 more locationsSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 1 - 60Code: NCT03970096·Phase 2·Recruiting·Listed May 2019Apply to this trial
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disordersfor Non-Neoplastic Hematopoietic and Lymphoid Cell Disorder1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: Up to 50Code: NCT03980769·Phase 2·Recruiting·Listed Jun 2019Apply to this trial
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancerfor Anatomic Stage IV Breast Cancer AJCC v81 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT05098210·Phase 1·Recruiting·Listed Oct 2021Apply to this trial
Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Diseasefor Intestinal Graft Versus Host Disease1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT05067595·Phase 1·Recruiting·Listed Oct 2021Apply to this trial
CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemiafor Recurrent Acute Myeloid Leukemia1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT04375631·Phase 1·Recruiting·Listed May 2020Apply to this trial
Improving Uptake of Surveillance in Colorectal Cancer Survivors Through Navigation and Web Educationfor Stage I Colorectal Cancer AJCC v82 locations in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT06995924·Recruiting·Listed May 2025Apply to this trial
Polatuzumab Vedotin and Combination Chemotherapy With or Without Glofitamab for the Treatment of Untreated Aggressive Large B-cell Lymphomafor Aggressive Non-Hodgkin LymphomaDrug: Polatuzumab Vedotin1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT04231877·Phase 1·Recruiting·Listed Jan 2020Apply to this trial
ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphomafor Recurrent Diffuse Large B-Cell Lymphoma1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT07098364·Phase 1, Phase 2·Recruiting·Listed Aug 2025Apply to this trial
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trialfor Bladder Cancer1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06040762·Recruiting·Listed Sep 2023Apply to this trial
Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancerfor Acute Leukemia of Ambiguous Lineage1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+Code: NCT07046078·Phase 2·Recruiting·Listed Jul 2025Apply to this trial
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancerfor Castration-Resistant Prostate CarcinomaSites in Seattle +2 more locationsSponsor: University of WashingtonSex: Male·Age: 18+Code: NCT04489719·Recruiting·Listed Jul 2020Apply to this trial
Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemiafor Acute Myeloid Leukemia1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT06710418·Recruiting·Listed Nov 2024Apply to this trial
A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trialfor Cigarette Smoking-Related Carcinoma1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06145763·Recruiting·Listed Nov 2023Apply to this trial
Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancerfor Castration-Resistant Prostate CarcinomaDrug: Vorinostat1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: Male·Age: All agesCode: NCT06145633·Phase 2·Recruiting·Listed Nov 2023Apply to this trial
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseasesfor Acute Leukemia of Ambiguous Lineage1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 6 Months - 65Code: NCT06013423·Phase 2·Recruiting·Listed Aug 2023Apply to this trial
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancerfor Localized Renal Pelvis and Ureter Urothelial Carcinoma1 location in SeattleSponsor: University of WashingtonSex: Male·Age: 18+·Accepts healthy volunteersCode: NCT01050504·Recruiting·Listed Jan 2010Apply to this trial
PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancerfor Metastatic Lung Non-Small Cell Carcinoma1 location in SeattleSponsor: University of WashingtonSex: All·Age: 18+Code: NCT04151940·Recruiting·Listed Nov 2019Apply to this trial
Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Studyfor Castration-Resistant Prostate Carcinoma1 location in SeattleSponsor: University of WashingtonSex: Male·Age: 18+Code: NCT06039371·Phase 2·Recruiting·Listed Sep 2023Apply to this trial
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosisfor Primary Myelofibrosis1 location in SeattleSponsor: Fred Hutchinson Cancer CenterSex: All·Age: 18 - 70Code: NCT04370301·Phase 2·Recruiting·Listed Apr 2020Apply to this trial