Paid Clinical Trials in Tennessee

Tennessee has 2,163 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,163 clinical trials

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Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes

for Open Angle Glaucoma

15 locations incl. Newport Beach

Sponsor: Iantrek, Inc.

Sex: All·Age: 21+

Code: NCT05506423·Enrolling By Invitation

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

Drug: Mavacamten

62 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting

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A Study of XMT-1660 in Participants With Solid Tumors

for Triple Negative Breast Cancer

26 locations incl. Phoenix

Sponsor: Mersana Therapeutics

Sex: All·Age: 18+

Code: NCT05377996·Phase 1·Recruiting

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A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

for Lymphoma, Non-Hodgkin

14 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05421663·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT

for Acute Ischemic Stroke

1 location in Chattanooga

Sponsor: Lumosa Therapeutics Co., Ltd.

Sex: All·Age: 18 - 90

Code: NCT05198323·Phase 2·Recruiting

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

51 locations incl. Mobile

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

for Non Small Cell Lung Cancer

6 locations incl. Huntersville

Sponsor: Phanes Therapeutics

Sex: All·Age: 18+

Code: NCT05431270·Phase 1, Phase 2·Recruiting

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Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

for Pancreatic Cancer Metastatic

14 locations incl. Hot Springs

Sponsor: Panbela Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05254171·Phase 2, Phase 3·Recruiting

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Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

for Cardiac Arrest, Out-Of-Hospital

50 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 2 Days - 17

Code: NCT05376267·Recruiting

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

165 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting

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A Study of D3S-001 Monotherapy or Combination Therapy in Subjects With Advanced Solid Tumors With a KRAS p.G12C Mutation

for KRAS P.G12C

7 locations incl. Orange

Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All·Age: 18+

Code: NCT05410145·Phase 1, Phase 2·Recruiting

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Rett Syndrome Registry

for Rett Syndrome

18 locations incl. Birmingham

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting

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Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

for Beta-Thalassemia

3 locations incl. New York

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 12 - 35

Code: NCT05477563·Phase 3·Recruiting

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A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

for Advanced or Metastatic Colorectal Cancer

Drug: Amivantamab

14 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05379595·Phase 1, Phase 2·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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Discarded Bone Marrow for Hematology Research

for Hemoglobinopathies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04671212·Recruiting

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Robotic Versus Open Ventral Hernia Repair

for Ventral Hernia

4 locations incl. Gainesville

Sponsor: Lucas Beffa

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05472987·Recruiting

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A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

19 locations incl. Anaheim

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting

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Otoferlin Gene-mediated Hearing Loss Natural History Study

for Sensorineural Hearing Loss, Bilateral

4 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: Up to 44

Code: NCT05572073·Recruiting

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Cooperative Assessment of Late Effects for SCD Curative Therapies

for Sickle Cell Disease

5 locations incl. Washington D.C.

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 4 - 65

Code: NCT05153967·Recruiting

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Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

for Advanced Cancer

14 locations incl. Scottsdale

Sponsor: Riboscience, LLC.

Sex: All·Age: 18+

Code: NCT05270213·Phase 1·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for Pediatric Solid Tumor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04897321·Phase 1·Recruiting

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Study of INCB123667 in Subjects With Advanced Solid Tumors

for Solid Tumors

Drug: INCB123667

19 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05238922·Phase 1·Recruiting

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A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

for Melanoma

31 locations incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 16+

Code: NCT05355701·Phase 1·Recruiting

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Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for Acute Respiratory Distress Syndrome

32 locations incl. Phoenix

Sponsor: Direct Biologics, LLC

Sex: All·Age: 18 - 75

Code: NCT05354141·Phase 3·Recruiting

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Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

for Glaucoma, Open-Angle

9 locations incl. Newport Beach

Sponsor: Amneal Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT05401357·Phase 3·Recruiting

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Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

for Advanced Extrapulmonary Neuroendocrine Carcinoma

Drug: Atezolizumab

250 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05058651·Phase 2, Phase 3·Recruiting

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Ultrafiltration Versus IV Diuretics in Worsening Heart Failure

for Heart Failure (for Example, Fluid Overload)

17 locations incl. Tucson

Sponsor: Nuwellis, Inc.

Sex: All·Age: 18+

Code: NCT05318105·Recruiting

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MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms

for Myopia

30 locations incl. Birmingham

Sponsor: CooperVision, Inc.

Sex: All·Age: 8 - 12·Accepts healthy volunteers

Code: NCT05285553·Recruiting

Apply to this trial

CPAP for the Treatment of Supine Hypertension

for Autonomic Failure

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40 - 80

Code: NCT05489575·Recruiting

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GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

58 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting

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Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

for Marginal Zone Lymphoma

4 locations incl. Duarte

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05296070·Phase 2·Recruiting

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A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

for Amyloid Plaque

13 locations incl. Phoenix

Sponsor: AC Immune SA

Sex: All·Age: 35 - 85

Code: NCT05462106·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

for B-Cell Non-Hodgkin Lymphoma

25 locations incl. Clovis

Sponsor: ADC Therapeutics S.A.

Sex: All·Age: 18+

Code: NCT04970901·Phase 1·Recruiting

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A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

for Non-Hodgkin Lymphoma

Drug: Epcoritamab

18 locations incl. Tucson

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05283720·Phase 2·Recruiting

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Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

20 locations incl. Phoenix

Sponsor: Xencor, Inc.

Sex: All·Age: 18+

Code: NCT05433142·Phase 1·Recruiting

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An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus (SLE)

36 locations incl. Phoenix

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05352919·Phase 3·Enrolling By Invitation

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

for Mesothelioma

25 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05245500·Phase 1·Recruiting

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A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for Locally Advanced Solid Tumor

21 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05384626·Phase 1, Phase 2·Recruiting

Apply to this trial