Paid Clinical Trials in Tennessee

Tennessee has 2,163 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,163 clinical trials

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Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

for Acute Stroke

35 locations incl. Fairhope

Sponsor: DiaMedica Therapeutics Inc

Sex: All·Age: 18 - 90

Code: NCT05065216·Phase 2, Phase 3·Recruiting

Apply to this trial

Desara ® One Single Incision Sling 522 Study

for Stress Urinary Incontinence

15 locations incl. Phoenix

Sponsor: Caldera Medical, Inc.

Sex: Female·Age: 18+

Code: NCT04772131·Recruiting

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PHACE - Prospective Genetic Investigation

for PHACE Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT05133245·Enrolling By Invitation

American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

16 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting

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Tennessee Alzheimer's Project

for Aging

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05372172·Recruiting

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First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Non-small Cell Lung Cancer

11 locations incl. Gilbert

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT05099172·Phase 1, Phase 2·Recruiting

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A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for Metastatic Colorectal Cancer

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04929223·Phase 1·Recruiting

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A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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Multi-Center Clinical Database of Infants for the Investigation of Early Nutrition Biomarkers

for Infant Development

9 locations incl. Birmingham

Sponsor: ByHeart

Sex: All·Age: 0 Days - 5

Code: NCT05049655·Enrolling By Invitation

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

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Trial of Vision Therapy for Intermittent Exotropia

for Intermittent Exotropia

6 locations incl. Birmingham

Sponsor: Southern California College of Optometry at Marshall B. Ketchum University

Sex: All·Age: 8 - 16

Code: NCT04487249·Recruiting

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Longitudinal Impact of Stressors in Adults With Tourette Syndrome

for Tourette Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04851678·Recruiting

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Implementing Inclusive Fraction Intervention Classwide

for Math Learning Difficulty

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 8 - 11·Accepts healthy volunteers

Code: NCT04878757·Enrolling By Invitation

Innovations in Genicular Outcomes Registry

for Knee Osteoarthritis

19 locations incl. Phoenix

Sponsor: Pacira Pharmaceuticals, Inc

Sex: All·Age: All ages

Code: NCT05495334·Recruiting

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RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

for ALK Fusion-positive Solid or CNS Tumors

7 locations incl. Palo Alto

Sponsor: Hoffmann-La Roche

Sex: All·Age: Up to 17

Code: NCT04774718·Phase 1, Phase 2·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

11 locations incl. Washington D.C.

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting

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ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

16 locations incl. Los Angeles

Sponsor: Zenith Epigenetics

Sex: Male·Age: 18+

Code: NCT04986423·Phase 2·Recruiting

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

28 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting

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Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

for Alagille Syndrome

18 locations incl. San Diego

Sponsor: Albireo, an Ipsen Company

Sex: All·Age: All ages

Code: NCT05035030·Phase 3·Recruiting

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

17 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting

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Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation

for Wilms Tumor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04968990·Phase 2·Recruiting

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Gut Microbiota in Metabolic Surgery

for Bariatric Surgery Candidate

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 21 - 65

Code: NCT05000996·Recruiting

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Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

for Down Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT05231798·Phase 2·Recruiting

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Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

10 locations incl. La Jolla

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05007782·Phase 1·Recruiting

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A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

for Adenovirus Infections

11 locations incl. Los Angeles

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT04706923·Phase 2·Recruiting

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EBT Fruit and Vegetable Prescription

for Childhood Obesity

2 locations incl. Knoxville

Sponsor: The University of Tennessee, Knoxville

Sex: All·Age: 4 - 10·Accepts healthy volunteers

Code: NCT05028205·Recruiting

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Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

for Nephrolithotomy, Percutaneous

1 location in Knoxville

Sponsor: University of Tennessee Medical Center

Sex: All·Age: 18+

Code: NCT05024344·Recruiting

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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

for Adult Spinal Deformity

12 locations incl. Phoenix

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04885244·Recruiting

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EFS of the CardioMech MVRS

for Mitral Regurgitation

12 locations incl. Thousand Oaks

Sponsor: CardioMech AS

Sex: All·Age: 18+

Code: NCT04820764·Recruiting

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A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

29 locations incl. Birmingham

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT04976322·Phase 3·Enrolling By Invitation

Neural Correlates of Sensory Phenomena in Tourette Syndrome

for Tourette Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03914664·Enrolling By Invitation

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

8 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting

Apply to this trial