Paid Clinical Trials in Tennessee

Tennessee has 2,163 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,163 clinical trials

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

25 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

25 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting

Apply to this trial

Global Utilization And Registry Database for Improved heArt preservatioN

for Heart Diseases

17 locations incl. Stanford

Sponsor: Paragonix Technologies

Sex: All·Age: All ages

Code: NCT04141605·Enrolling By Invitation

Indocyanine Green (ICG) Guided Tumor Resection

for Neoplastic Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04084067·Phase 1·Recruiting

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[18F]F-DOPA Imaging in Patients With Autonomic Failure

for Autonomic Failure

1 location in Nashville

Sponsor: Daniel Claassen

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04246437·Phase 1·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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The U.S. PDA Registry

for Ductus Arteriosus, Patent

1 location in Memphis

Sponsor: Le Bonheur Children's Hospital

Sex: All·Age: 3 Days - 1

Code: NCT04205877·Not Yet Recruiting

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

32 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting

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Disorders of the Acute Phase Response Following Trauma and Invasive Surgery

for Acute Phase Response

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 2 Months+·Accepts healthy volunteers

Code: NCT03741023·Enrolling By Invitation

Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

for Open Midline Laparotomy

31 locations incl. Phoenix

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT03911700·Recruiting

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

73 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)

for Vertebral Artery Stenosis

10 locations incl. Jacksonville

Sponsor: St. Louis University

Sex: All·Age: 18 - 90

Code: NCT03999983·Recruiting

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Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

for Advanced Solid Tumor

15 locations incl. Los Angeles

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT04145622·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

for B-cell Acute Lymphoblastic Leukemia

14 locations incl. Los Angeles

Sponsor: Cellectis S.A.

Sex: All·Age: 15 - 50

Code: NCT04150497·Phase 1, Phase 2·Recruiting

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Von Willebrand Factor in Pregnancy (VIP) Study

for Von Willebrand Diseases

11 locations incl. Aurora

Sponsor: University of Washington

Sex: Female·Age: 18+

Code: NCT04146376·Recruiting

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A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

for Acute Myeloid Leukemia

21 locations incl. Fountain Valley

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04093570·Phase 2·Enrolling By Invitation

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

101 locations incl. Birmingham

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

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Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for Smoldering Plasma Cell Myeloma

Drug: Daratumumab

741 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03937635·Phase 3·Recruiting

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Non-invasive Markers of Esophageal Function in Adults

for Dysphagia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04074356·Enrolling By Invitation

Comparative Effectiveness of IIMR Versus CDSMP

for Mental Illness

2 locations incl. Louisville

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18+

Code: NCT03966872·Recruiting

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Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients

for Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG

10 locations incl. Chicago

Sponsor: Theralase® Technologies Inc.

Sex: All·Age: 18+

Code: NCT03945162·Phase 2·Recruiting

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Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

for Glioma

2 locations incl. Rochester

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 21

Code: NCT04065776·Recruiting

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Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy

for Back Pain Without Radiation

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40+

Code: NCT03912519·Enrolling By Invitation

Executive Function in Early Childhood

for Reading Disability

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 4 - 9·Accepts healthy volunteers

Code: NCT03713125·Recruiting

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A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

for Myelodysplastic Syndromes (MDS)

12 locations incl. Los Angeles

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT04064060·Phase 3·Recruiting

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Pan Tumor Rollover Study

for Cancer

59 locations incl. Huntsville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

45 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting

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Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for Metastatic Uveal Melanoma

12 locations incl. Los Angeles

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT03947385·Phase 1, Phase 2·Recruiting

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Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

for Clinical Stage I Esophageal Adenocarcinoma AJCC v8

95 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03801876·Phase 3·Recruiting

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Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

for Neovascular Age-related Macular Degeneration

9 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT03999801·Phase 2·Enrolling By Invitation

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

49 locations incl. Duarte

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting

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Botox or Botox With Esophageal Dilation in Patients With Achalasia

for Achalasia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT03654066·Phase 4·Enrolling By Invitation

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

579 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting

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Sensory Symptoms in Tourette Syndrome

for Tourette Syndrome

2 locations incl. Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT03851484·Recruiting

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Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

18 locations incl. Tucson

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting

Apply to this trial