Clinical Trials at Children's National Hospital

As of September 2026, 70 paid clinical trials are recruiting at Children's National Hospital, located at Children's National Hospital, 111 Michigan Ave NW, Washington, DC 20010, phone (888) 884-2327 in Washington D.C., District of Columbia. Active studies at this site cover conditions such as Breast Cancer, Sickle Cell Disease and Stroke. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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Healthy volunteers only

Newly added in Washington D.C.

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

Pupillary Dilation Reflex in Healthy Volunteers

for Healthy Participants

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07746167·Recruiting·Listed Aug 4, 2026

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71 clinical trials at Children's National Hospital

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

Sites in Washington D.C. +31 more locations

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting·Listed Feb 2026

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

Sites in Washington D.C. +21 more locations

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025

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Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

for GRIN-related Neurodevelopmental Disorder

Sites in Washington D.C. +16 more locations

Sponsor: GRIN Therapeutics, Inc.

Sex: All·Age: 1 Month - 18

Code: NCT07224581·Phase 3·Recruiting·Listed Nov 2025

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A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for T-cell Acute Lymphoblastic Leukemia

Sites in Washington D.C. +14 more locations

Sponsor: Allotera Therapeutics

Sex: All·Age: 1+

Code: NCT06514794·Phase 2·Recruiting·Listed Jul 2024

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REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome

for Angelman Syndrome

Sites in Washington D.C. +17 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting·Listed Apr 2025

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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

for Neurofibromatosis Type 1

Sites in Washington D.C. +13 more locations

Sponsor: Healx Limited

Sex: All·Age: 12+

Code: NCT06541847·Phase 2·Recruiting·Listed Aug 2024

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Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

Sites in Washington D.C. +11 more locations

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting·Listed Dec 2024

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Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

for Familial Hypercholesterolemia - Heterozygous

Drug: Inclisiran

Sites in Washington D.C. +10 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 6 - 11

Code: NCT06597019·Phase 3·Recruiting·Listed Sep 2024

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Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

for Refractory Ewing Sarcoma

Drug: Lurbinectedin

Sites in Washington D.C. +13 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 2 - 30

Code: NCT05734066·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study

for Intra Abdominal Infections

1 location in Washington D.C.

Sponsor: True Bearing Diagnostics, Inc.

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07579312·Recruiting·Listed May 2026

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A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

for Duchene Muscular Dystrophy

Drug: Givinostat

Sites in Washington D.C. +8 more locations

Sponsor: ITF Therapeutics LLC

Sex: All·Age: 6+

Code: NCT07127978·Recruiting·Listed Aug 2025

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Prospective Clinical Assessment Study in Children With Hypochondroplasia

for Hypochondroplasia

Sites in Washington D.C. +7 more locations

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 30 Months - 16

Code: NCT06410976·Recruiting·Listed May 2024

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Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy

for Allergic Reactions

Sites in Washington D.C. +5 more locations

Sponsor: ARS Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06834165·Phase 4·Recruiting·Listed Feb 2025

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An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

for Hyperammonemia

Sites in Washington D.C. +4 more locations

Sponsor: RECORDATI GROUP

Sex: All·Age: All ages

Code: NCT05040178·Recruiting·Listed Sep 2021

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Non-invasive Central Venous Pressure Estimation in Pediatric Patients

for Central Venous Pressure

1 location in Washington D.C.

Sponsor: Compremium AG

Sex: All·Age: Up to 21

Code: NCT06885073·Recruiting·Listed Mar 2025

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Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

Sites in Washington D.C. +23 more locations

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting·Listed Feb 2026

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Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

for Rhabdomyosarcoma

2 locations in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 1 - 23

Code: NCT07172958·Phase 1·Recruiting·Listed Sep 2025

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

Sites in Washington D.C. +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting·Listed Aug 2025

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A Feasibility Study to Evaluate Safety and Probable Benefit of the Eclipse XL1 System for Distraction Enterogenesis in Adult and Pediatric Patients With Short Bowel Syndrome

for Short Bowel Syndrome

Sites in Washington D.C. +4 more locations

Sponsor: Eclipse Regenesis, Inc.

Sex: All·Age: 3 Months - 65

Code: NCT05535361·Recruiting·Listed Sep 2022

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Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

for Medulloblastoma

Sites in Washington D.C. +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 39

Code: NCT05057702·Recruiting·Listed Sep 2021

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in Washington D.C. +19 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Washington D.C. +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

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Family Intervention for Black Teens With Type 1 Diabetes

for Type 1 Diabetes

Sites in Washington D.C. +3 more locations

Sponsor: Wayne State University

Sex: All·Age: 10 - 14

Code: NCT06275412·Recruiting·Listed Feb 2024

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Characterization of Acute Pain

for Acute Pain, Postoperative

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 6 - 21

Code: NCT07336264·Recruiting·Listed Jan 2026

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Washington D.C. +15 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

for Recurrent Group 3 Medulloblastoma

Sites in Washington D.C. +1 more location

Sponsor: University of Florida

Sex: All·Age: 4 - 30

Code: NCT06514898·Phase 1·Recruiting·Listed Jul 2024

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Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

for Solid Tumor

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 1 - 70

Code: NCT05238792·Phase 1·Recruiting·Listed Feb 2022

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International Rare Brain Tumor Registry

for Astroblastoma

Sites in Washington D.C. +5 more locations

Sponsor: Children's National Research Institute

Sex: All·Age: Up to 45

Code: NCT05697874·Recruiting·Listed Jan 2023

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Health-E You Efficacy Trial for Male Adolescents

for Sexually Transmitted Diseases

Sites in Washington D.C. +7 more locations

Sponsor: Johns Hopkins University

Sex: Male·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06525064·Recruiting·Listed Jul 2024

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MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

for Low Grade Glioma

Sites in Washington D.C. +2 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 1 - 26

Code: NCT06712875·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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ARPKD Database Study

for Hepato/Renal Fibrocystic Disease

Sites in Washington D.C. +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT01401998·Recruiting·Listed Jul 2011

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Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study

for ADPKD

Sites in Washington D.C. +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT04338048·Recruiting·Listed Apr 2020

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A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

for Adult Glioblastoma

Sites in Washington D.C. +1 more location

Sponsor: University of Florida

Sex: All·Age: 4+

Code: NCT04573140·Phase 1·Recruiting·Listed Oct 2020

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Navigating Pregnancy and Parenthood With Lyme Disease

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: Female·Age: 18+

Code: NCT06397794·Recruiting·Listed May 2024

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Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

for Medulloblastoma, Childhood

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 1 - 30

Code: NCT06193759·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 18+

Code: NCT06026969·Recruiting·Listed Sep 2023

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

Sites in Washington D.C. +4 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting·Listed Feb 2021

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Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

for Cerebral Palsy, Dyskinetic

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 8 - 22

Code: NCT06036199·Recruiting·Listed Sep 2023

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

Sites in Washington D.C. +14 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting·Listed Jan 2024

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A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.

for CNS Malignancies

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 3 - 21

Code: NCT07017816·EARLY_Phase 1·Recruiting·Listed Jun 2025

Apply to this trial

Common conditions studied in Washington D.C.

Breast Cancer (15 active studies)
Sickle Cell Disease (12 active studies)
Stroke (11 active studies)
Heart Failure (9 active studies)
Obesity (9 active studies)
Prostate Cancer (9 active studies)

Leading research sponsors in Washington D.C.

Children's National Research Institute
Georgetown University
National Cancer Institute (NCI)
George Washington University
Medstar Health Research Institute

Frequently asked questions

How many paid clinical trials are currently recruiting in Washington D.C.?

There are approximately 844 recruiting clinical trials in Washington D.C., District of Columbia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Washington D.C. pay participants?

Most recruiting trials in Washington D.C. compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Washington D.C.?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Washington D.C.?

The most common conditions under active study in Washington D.C. include Breast Cancer (15), Sickle Cell Disease (12), Stroke (11), Heart Failure (9), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Washington D.C.?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Washington D.C. on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Washington D.C.?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Washington D.C.?

Recruiting research sites in Washington D.C. include MedStar Washington Hospital Center, Children's National Medical Center, Children's National Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Washington D.C. right now?

The largest active categories in Washington D.C. are Cancer & tumors (292), Neurology & pain (65), Cardiovascular (52). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

What is the address of Children's National Hospital?

Children's National Hospital is located at Children's National Hospital, 111 Michigan Ave NW, Washington, DC 20010. Use the Google Maps link in the intro above to get directions.

How do I contact Children's National Hospital?

You can reach Children's National Hospital by phone at (888) 884-2327. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.

Browse more clinical trials

Other cities in District of Columbia

Georgetown, DC(1)Washinton, DC(1)

Related healthcare resources in District of Columbia

Latest Washington D.C., DC clinical trials research report

Trials by condition in Washington D.C.

Breast Cancer· 15 Sickle Cell Disease· 12 Stroke· 11 Heart Failure· 9 Obesity· 9 Prostate Cancer· 9