Effect of Ranibizumab on Malignant Conjunctival Neoplasia

Part of paid clinical trials in New York, New York.

Sponsor
The New York Eye Cancer Center
Study ID
NCT00456495
Phase
PHASE1
Status
Completed

Conditions

  • Conjunctival Neoplasms

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ranibizumab — DRUG
    Subconjunctival injection of drug every 2 to 4 weeks

Study Details

The purpose of this study is to test the safety and tolerability of subconjunctival injection of ranibizumab in the treatment of malignant conjunctival neoplasia using the incidence and severity of adverse events. Our secondary objective is to assess the efficacy of ranibizumab treatment on malignant conjunctival neoplasia by evaluating tumor destruction or reduction as documented by slit-lamp photography and ultrasonographic imaging and the regression of blood vessels.

Key Dates

First listed
Apr 5, 2007
Start date
Mar 31, 2007
Status verified
Jun 2017
Primary completion
Sep 30, 2010
Completion
Sep 30, 2010

Study Design

Enrollment
5 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Subconjunctival ranibizumab
    Patients will receive subconjunctival ranibizumab every 2-4 weeks.

Primary Outcome Measure

Number of Patients Assessed for Safety and Tolerability [ Time Frame: 2 years ]

Locations (1)

FacilityCityStateZIPSite coordinators
The New York Eye Cancer CenterNew YorkNew York10021-

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