Trial to Evaluate the Efficacy and Safety of Tarceva and Capecitabine in Advanced Pancreatic Cancer Patients

Sponsor
Grupo Gallego de Investigaciones Oncologicas
Study ID
NCT00873353
Phase
PHASE2
Status
Completed

Conditions

  • Metastatic Adenocarcinoma of the Pancreas

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • capecitabine + erlotinib — DRUG
    6 cycles (3 weeks each one) of : * capecitabine 1000mg/m2, bid, oral. Days: 1-14 every three weeks * erlotinib (Tarceva®) 150mg/day, oral. Days: every days

Study Details

The purpose of this study is to determine efficacy of the treatment with erlotinib in combination with capecitabine in patients with advanced pancreatic cancer.

Key Dates

First listed
Apr 1, 2009
Start date
Mar 31, 2008
Status verified
Aug 2010
Primary completion
Aug 31, 2008
Completion
Aug 31, 2010

Study Design

Enrollment
32 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Unique arm
    6 cycles (3 weeks each one) of : * capecitabine 1000mg/m2, bid, oral. Days: 1-14 every three weeks * erlotinib (Tarceva®) 150mg/day, oral. Days: every days

Primary Outcome Measure

Objective response rate following RECIST criteria [ Time Frame: within study period ]