Comparison of Intravitreal Ranibizumab and Macular Laser Photocoagulation for ME Following Branch Retinal Vein Occlusion (BRVO)
- Sponsor
- Seoul Retina Investigator Group
- Study ID
- NCT01189526
- Phase
- PHASE3
- Status
- Unknown
Conditions
- Branch Retinal Vein Occlusion
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Ranibizumab — DRUGRanibizumab 0.5mg Ranibizumab will be administered to patients as multiple intravitreal injections.
- macular laser photocoagulation — PROCEDURETreatment may include both focal and grid therapy using the laser and contact lens of the investigator's choice.
Study Details
This study is designed to evaluate the efficacy of intravitreal Ranibizumab in comparison with macular laser photocoagulation as treatments for macular edema secondary to branch retinal vein occlusion. Characteristics of this study is as below 1. Multicenter, randomized clinical trial. (intravitreal Ranibizumab 0.5mg injection vs. macular laser photocoagulation) 2. After 48 weeks follow up, functional change(visual acuity)and anatomical change (central retinal thickness) would be evaluated
Key Dates
- First listed
- Aug 26, 2010
- Start date
- Jan 31, 2009
- Status verified
- Aug 2010
- Primary completion
- Aug 31, 2010
- Completion
- Aug 31, 2011
Study Design
- Enrollment
- 60 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: IVRIIVRI : intravitreal ranibizumab (0.5mg) injection
- Active Comparator: LaserLaser : macular laser photocoagulation
Primary Outcome Measure
Best Corrected Visual Acuity (ETDRS letters) [ Time Frame: 48 weeks ]
Central Contacts
- Song Ee Chung, M.D.
- Yun Taek Kim, M.D.