Treatment of Female Genital Erosive Lichen Planus(GELP) With Hexaminolevulinate PDT

Sponsor
Oslo University Hospital
Study ID
NCT01282515
Phase
PHASE2/PHASE3
Status
Completed

Conditions

  • Genital Lichen Planus

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • clobetasol propionate 0,05% ointment — DRUG
    continuously daily treatment for 6 weeks
  • hexaminolevulinate — DRUG
    one PDT treatment

Study Details

To compare the effect and side effects of photodynamic treatment and traditional topical steroid treatment in female genital erosive lichen planus

Key Dates

Start date
Aug 31, 2011
Status verified
Mar 2021
Primary completion
Oct 31, 2014
Completion
Oct 31, 2014

Study Design

Enrollment
40 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: ELP active
    one PDT treatment with 2 ml hexaminolevulinate 6 mg/ml gel
  • Active Comparator: topical steroids
    treatment with clobetasol propionate 0.05% ointment used daily for 6 weeks

Primary Outcome Measure

Percentage change of GELP score and/or VAS score 6 weeks after start of treatment. [ Time Frame: 6 weeks ]