Study to Evaluate Efficacy and Tolerance of R-GemOx in DLBCL and MCL
- Sponsor
- Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
- Study ID
- NCT01562977
- Phase
- PHASE2
- Status
- Completed
Conditions
- Aggressive Lymphoma
- Diffuse Large B-cell Lymphoma
- Mantle Cell Lymphoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Rituximab, Gemcitabine, Oxaliplatin, Dexametasone — DRUGuntil progression or unacceptable toxicity develops, 8 cicles max Rituximab: 375 mg/m2, IV, day 1. Gemcitabine: 1000 mg/m2, IV, day 2. Oxaliplatin: 100 mg/m2, IV, day 2. Dexametasone: 20 mg/day, days 1-3, oral.
Study Details
The purpose of this study is to determine efficacy of rituximab, gemcitabine, oxaliplatin and dexametasone (R-GemOx) chemotherapy schedule.
Key Dates
- Start date
- Apr 30, 2011
- Status verified
- Oct 2017
- Primary completion
- Apr 30, 2015
- Completion
- Apr 30, 2015
Study Design
- Enrollment
- 82 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Other: no armsno arms were present for the study, only 2 different cohorts:MCL and LDCGB
Primary Outcome Measure
The primary endpoint is to evaluate Overall response rate (ORR) [ Time Frame: 3 years and 2 months ]
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