Rituximab in Systemic Sclerosis
- Sponsor
- Assistance Publique - Hôpitaux de Paris
- Study ID
- NCT01748084
- Phase
- PHASE2/PHASE3
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Rituximab — DRUGDays 1 and 15, rituximab 1 gramme plus 100 mg methylprednisolone
- Placebo (NaCl) — DRUGDays 1 and 15, NaCl 500 ml plus 100 mg methylprednisolone
Study Details
The purpose of this study is to determine whether rituximab is effective in the treatment of articular symptoms that occur in systemic sclerosis related polyarthritis
Key Dates
- Start date
- Apr 9, 2013
- Status verified
- Oct 2025
- Primary completion
- Apr 18, 2016
- Completion
- Apr 18, 2016
Study Design
- Enrollment
- 22 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Placebo Comparator: NaClNaCl 500 ml IV day 1 and day 15 plus 100 mg methylprednisolone
- Experimental: RituximabRituximab 1G IV day 1 and day 15 plus 100 mg methylprednisolone
Primary Outcome Measure
Number of tender and swollen joints [ Time Frame: at 6 months ]
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