Erlotinib 100mg or 150mg in Treating EGFR Mutated NSCLC
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
- Study ID
- NCT02140333
- Phase
- PHASE3
- Status
- Unknown
Conditions
- EGFR Mutation
- NSCLC
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Erlotinib — DRUG100mg vs. 150mg
Study Details
The purpose of this study is to determine whether 100mg erlotinib had similar effect compared with 150mg erlotinib in NSCLC patients with EGFR mutation in China.
Key Dates
- First listed
- May 16, 2014
- Start date
- Aug 31, 2013
- Status verified
- Feb 2015
- Primary completion
- Aug 31, 2018
- Completion
- Dec 31, 2018
Study Design
- Enrollment
- 220 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Erlotinib 100mgErlotinib 100mg
- Active Comparator: Erlotinib 150mgErlotinib 150mg
Primary Outcome Measure
Progression free survival [ Time Frame: 2 years after the initial dose ]
Central Contacts
- jianxing He, PhD86-20-83062821
- yalei zhang, Dr.86-20-83062821
Related Studies
- APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsPHASE2 · Recruiting · Apollomics Inc. · Los Angeles, California
- A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsPHASE1/PHASE2 · Recruiting · Merus B.V. · La Jolla, California
- A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung CancerPHASE1/PHASE2 · Recruiting · Regeneron Pharmaceuticals · Birmingham, Alabama
- Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor MalignanciesPHASE2 · Recruiting · Dan Zandberg · Pittsburgh, Pennsylvania