Evaluation of the Usefulness of a PRN Regimen Using Ranibizumab for Macular Edema Due to Branch Retinal Vein Occlusion

Sponsor
Nagoya City University
Study ID
NCT02478515
Phase
PHASE4
Status
Completed

Conditions

  • Branch Retinal Vein Occlusion

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ranibizumab — DRUG
    Intraviteal injection of 0.5mg ranibizumab

Study Details

Monthly intravitreal ranibizumab (IVR) during the first 6 month had great effect for macular edema with branch retinal vein occlusion (BVO) both in visual and anatomical outcome. It is expected that similar results could be obtained by less frequent IVR. The purpose of this study is to investigate if IVR by PRN is as effective as by monthly. In addition, the investigators are going to study the relationship between macular edema and the size and location of retinal non-perfusion area.

Key Dates

First listed
Jun 23, 2015
Start date
Jan 31, 2014
Status verified
Oct 2016
Primary completion
Mar 31, 2019
Completion
Mar 31, 2019

Study Design

Enrollment
27 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Intraviteal Ranibizumab 0.5mg
    Intraviteal Ranibizumab 0.5mg

Primary Outcome Measure

Visual acuity [ Time Frame: One years ]