Pharmacokinetics and Safety Study of ASKB1202 in Chinese Healthy Subjects
- Sponsor
- Jiangsu Aosaikang Pharmaceutical Co., Ltd.
- Study ID
- NCT03115762
- Phase
- PHASE1
- Status
- Unknown
Conditions
- Healthy
Eligibility Criteria
- Sex
- MALE
- Age
- 18 Years - 50 Years
- Healthy Volunteers
- Accepted
Interventions
- bevacizumab — BIOLOGICALrecombinant humanized monoclonal antibody produced by DNA technology in Chinese Hamster Ovary cells
- ASKB1202 — BIOLOGICAL
Study Details
This trial will investigate the pharmacokinetic,immunogenicity and safety biosimilarity of ASKB1202 compared to bevacizumab sold in China and Europe.
Key Dates
- First listed
- Apr 14, 2017
- Start date
- Jun 30, 2017
- Status verified
- Apr 2017
- Primary completion
- Jul 31, 2017
- Completion
- Jul 31, 2017
Study Design
- Enrollment
- 126 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: ASKB1202Subject to receive one intravenous (i.v.) infusion of ASKB1202
- Active Comparator: bevacizumab ASubject to receive one intravenous (i.v.) infusion of bevacizumab sold in China
- Active Comparator: bevacizumab BSubject to receive one intravenous (i.v.) infusion of bevacizumab sold in Europe
Primary Outcome Measure
Cmax [ Time Frame: up to 100 days ]
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