Single and Multiple Ascending Dose Study of NGM120 in Healthy Adult Subjects
- Sponsor
- NGM Biopharmaceuticals, Inc
- Study ID
- NCT03392116
- Phase
- PHASE1
- Status
- Completed
Conditions
- Cachexia
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 65 Years
- Healthy Volunteers
- Accepted
Interventions
- NGM120 — BIOLOGICALSubcutaneous Injection
- Placebo — OTHERSubcutaneous Injection
Study Details
The purpose is to evaluate the safety, tolerability, and PK of NGM120 in healthy adult subjects
Key Dates
- First listed
- Jan 5, 2018
- Start date
- Jan 29, 2018
- Status verified
- Aug 2019
- Primary completion
- Jan 14, 2019
- Completion
- Mar 11, 2019
Study Design
- Enrollment
- 92 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- FACTORIAL
- Primary purpose
- TREATMENT
Arms
- Experimental: Part A: NGM120Single Dose
- Placebo Comparator: Part A: PlaceboSingle Dose
- Experimental: Part B: NGM120Multiple Dose
- Placebo Comparator: Part B: PlaceboMultiple Dose
Primary Outcome Measure
Part A Arm-Single Dose: Treatment Emergent Adverse events [ Time Frame: 28 days ]
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