Real World Study on Erlotinib/Gefitinib Combined With Bevacizumab in Advanced Non-aquamous Non-small Cell Lung Cancer
- Sponsor
- Hunan Province Tumor Hospital
- Study ID
- NCT03647592
- Status
- Unknown
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Erlotinib/Gefitinib combined with Bevacizumab — DRUGErlotlnib,150mg po qd/gefitinib 250mg po qd +Bevacizumab(15mg/kg),lvgtt,every 21 day ,evaluate every 2 months
Study Details
This study aims to explore the efficacy and safety of Erlotinib/Gefitinib combined with bevacizumab in the real world for advanced non-squamous cell lung cancer with EGFR mutation, explore new drug resistance mechanisms under the A+T regimen and consistency between plasma and tissue detection driving genes, and finally assess the predictive value of plasma dynamic detection driving gene mutation profiles in predicting disease. The role of disease progression risk.
Key Dates
- First listed
- Aug 27, 2018
- Start date
- Jun 1, 2018
- Status verified
- Dec 2023
- Primary completion
- Aug 31, 2024
- Completion
- Dec 1, 2025
Study Design
- Enrollment
- 30 participants (estimated)
Arms
- Arm: Cohorts 1patients with EGFR mutation-positive who received treatment of Erlotinib/Gefitinib Combined With Bevacizumab
Primary Outcome Measure
PFS [ Time Frame: Approximately 1 years ]
Central Contacts
- Yongchang Z MD, MD+8613873123436
- Yongchang Z MD, PhD+8613873123436
Related Studies
- The Effect of Beta-glucan in Non-Small Cell Lung CancerRecruiting · University of Louisville · Louisville, Kentucky
- Dabrafenib and/or Trametinib Rollover StudyPHASE4 · Recruiting · Novartis Pharmaceuticals · Scottsdale, Arizona
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryRecruiting · Massive Bio, Inc. · Birmingham, Alabama
- Tumor Cell and DNA Detection in the Blood, Urine, and Bone MarrowRecruiting · University of Missouri-Columbia · Columbia, Missouri